Evidence map›Paper›PMID 37154948›Full record

ArticleArchives of microbiology2023

Synergistic antimicrobial system based on nisin and α-hydroxy organic acids.

Hui Guo, Fengju Zhao, Bingshuang Lei, Wei Yang, Lili Guo, Junqing Qian

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hui GuoCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, Zhejiang Province, People's Republic of China. tggh635@163.com.
Fengju ZhaoCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, Zhejiang Province, People's Republic of China.
Bingshuang LeiCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, Zhejiang Province, People's Republic of China.
Wei YangCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, Zhejiang Province, People's Republic of China.
Lili GuoCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, Zhejiang Province, People's Republic of China.
Junqing QianCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, Zhejiang Province, People's Republic of China.
Zhejiang University of Technology · CN

Funding

Zhejiang Provincial Natural Science Foundation of China No. LY16C020005
6 · The paper itself

Abstract

Synergistic antimicrobial is a promising way to overcome microbial contamination in food and drugs. In the study, the synergistic effect between nisin and α-hydroxy organic acids on E. coli and S. aureus was investigated. The experimental results showed that the combined antibacterial ability of nisin-citric acid system was the most prominent. The FCI index also indicated that the combination of nisin and citric acid had synergistic effects on E. coli. When nisin was combined with citric acid, the inhibition rates of E. coli and S. aureus were increased to 4.43 and 1.49 times, respectively. Nisin-citric acid complex system could effectively slow down the proliferation of S. aureus and E. coli at lower concentrations, and can quickly destroy the cell membrane after 4 h of action. Therefore, the combination of nisin and citric acid is expected to be a potential solution for food and drug preservation.

Indexed as

Anti-Infective AgentsNisinAnti-Bacterial AgentsCitric AcidEscherichia coliFood PreservationMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsCitric AcidNisinCombination effectNisinSynergistic antimicrobial systemα-Hydroxy organic acids

Identifiers

PMID37154948
OpenAlexW4375954886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.