Evidence map›Paper›PMID 37154935›Full record

ArticleAnalytical and bioanalytical chemistry2023

Fluorescence turn-on detection of human serum albumin based on the assembly of gold nanoclusters and bromocresol green.

Wenxiang Xiao, Yaoxin Li, Yinan Xiong, ZhenCheng Chen, Hua Li

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wenxiang XiaoSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China. wenxiangxiao@126.com.
Yaoxin LiSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China.
Yinan XiongSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China.
ZhenCheng ChenGuangxi Colleges and Universities Key Laboratory of Biomedical Sensing and Intelligent Instrument, Guilin University of Electronic Technology, Guilin, 541004, China.
Hua LiSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China. lihua@guet.edu.cn.
Guilin University of Electronic Technology · CN

Funding

Guangxi Key Laboratory of Automatic Detection Technology and Instrument Foundation No. YQ17113National Natural Science Foundation of China No. 61761013National Natural Science Foundation of China No. 61864001Natural Science Foundation of Guangxi Province No. 2017GXNSFAA198116
6 · The paper itself

Abstract

As the most abundant protein in plasma, human serum albumin plays a vital role in physiological processes, such as maintaining blood osmotic pressure and carrying small-molecule ligands. Since the content of albumin in the human serum can reflect the status of liver and renal function, albumin quantitation is significant in clinical diagnosis. In this work, fluorescence turn-on detection of human serum albumin (HSA) had been performed based on the assembly of gold nanoclusters and bromocresol green. Gold nanoclusters (AuNCs) capped by reduced glutathione (GSH) were assembled with bromocresol green (BCG), and the assembly was used as a fluorescent probe for HSA. After BCG assembling, the fluorescence of gold nanoclusters was nearly quenched. In acidic solution, HSA can selectively bind to BCG on the assembly and recover the fluorescence of the solution. Based on this turn-on fluorescence, ratiometric HSA quantification was realized. Under optimal conditions, HSA detection by the probe possessed a good linear relationship in the range of 0.40-22.50 mg·mL

Indexed as

Metal NanoparticlesSerum Albumin, HumanBromcresol GreenFluorescent DyesGoldHumansSpectrometry, FluorescenceBromcresol GreenFluorescent DyesGoldSerum Albumin, HumanBromocresol greenFluorescence turn-on detectionFluorescent assemblyGold nanoclustersHuman serum albumin

Identifiers

PMID37154935
OpenAlexW4375864773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.