ReviewAntioxidants & redox signaling2024
Vitamin E/Coenzyme Q-Dependent "Free Radical Reductases": Redox Regulators in Ferroptosis.
Open access · greenAbstract readReview
In one paragraph
Review in Antioxidants & redox signaling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 19 citations in OpenAlex.
- The role of miRNA in modulating oxidative stress in preeclampsia: current knowledge.RNA biology · 2026Review
- Acute Thermal Elevation Alters Cellular Metabolic Activity, Redox Balance, and Iron Homeostasis in Butterfly Lizards (Animals : an open access journal from MDPI · 2026Article
- Mechanistic Modulation of Autophagy by Bioactive Natural Products: Implications for Human Aging and Longevity.Nutrients · 2026Review
- Metabolomic identification and analysis of potential biomarkers of febrile seizures.BMC pediatrics · 2026Article
- Ferroptosis associated with secondary brain damage induced by hypertensive underlying biological processes in intracerebral hemorrhage and therapeutic prospects.European journal of medical research · 2026Review
- Fueling Death: The Metabolic Control of Ferroptosis.Advances in experimental medicine and biology · 2026Review
- Ferroptosis suppressor protein 1-mediated ferroptosis suppression in sepsis: non-canonical antioxidant pathways, inflammatory regulation, and therapeutic perspectives.Frontiers in immunology · 2026Review
- Dual role of ferroptosis in embryonic development, cascade amplification regulatory mechanism and targeted intervention.Frontiers in cell and developmental biology · 2026Review
- The role of fat-soluble vitamins on bone metabolism and osteoporosis: a literature review.Annals of medicine · 2025Review
- Gut Microbiota and Its Metabolites Modulate Pregnancy Outcomes by Regulating Placental Autophagy and Ferroptosis.Antioxidants (Basel, Switzerland) · 2025Review
- Mitochondrial Damage and Autophagy Dysregulation in Alzheimer's Disease: Mechanisms and Therapeutic Opportunities.Neurochemical research · 2025Review
- Ferroptosis: a new target for depression prevention and treatment.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Modulating Ferroptosis in Aging: The Therapeutic Potential of Natural Products.Journal of aging research · 2025Review
- From bench to bedside: targeting ferroptosis and mitochondrial damage in the treatment of diabetic cardiomyopathy.Frontiers in endocrinology · 2025Review
- The Ubiquitous and Multifaceted Coenzyme Q.Antioxidants (Basel, Switzerland) · 2024Article
- Role of ferroptosis in radiation-induced soft tissue injury.Cell death discovery · 2024Review
- An AlphaFold Structure Analysis of COQ2 as Key a Component of the Coenzyme Q Synthesis Complex.Antioxidants (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Valerian E KaganCenter for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-7245-1885
Adam C StraubDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Yulia Y TyurinaCenter for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Alexandr A KapralovCenter for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Robert HallDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Sally E WenzelDepartment of Environmental Health and Pharmacology and Chemical Biology and University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Rama K MallampalliDepartment of Internal Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Hülya BayirCenter for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2361-4120
University of Pittsburgh · USThe Ohio State University · US
Funding
Regulation of Cardiolin Byosynthesis in Epithelial InjuryP01HL114453 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MALLAMPALLI, RAMA K · 2014 to 2023
$21.3MBasic and Translational Studies in Redox Regulation of Cardiovascular Physiology and DiseaseR35HL161177 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Adam Carl Straub · 2022 to 2026
$4.7MLipids and Myeloid Cell Function in CancerR01CA165065 · NCI · WISTAR INSTITUTE · PI KAGAN, VALERIAN E, MONTANER, LUIS J · 2012 to 2022
$3.8MProtein-Oxidized Phospholipid Interactions Determine Epithelial Cell Fate and Asthma Control R01AI145406 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sally E Wenzel · 2020 to 2026
$2.9MRegulation of tumor recurrence by stress activated neutrophilsR01CA243142 · NCI · WISTAR INSTITUTE · PI ZHANG, RUGANG · 2020 to 2025
$2.8MRadiation Mitigators Targeting Regulated Necrosis Pathways of Parthanatos PyroptosisU01AI156923 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAYIR, HÜLYA · 2020 to 2024
$2.4MSelective Inhibitors of Pro-Ferroptotic Lipoxygenases - Next Generation RadiomitigatorsU01AI156924 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAGAN, VALERIAN E · 2020 to 2024
$2.3MPredoctoral Training in Pharmacological Sciences (Resubmission)T32GM133332 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tija C. Jacob, Francisco Jose Schopfer · 2020 to 2026
$1.8MNCI NIH HHS R01 CA165065NCI NIH HHS R01 CA243142NHLBI NIH HHS P01 HL114453NHLBI NIH HHS R35 HL161177NIAID NIH HHS R01 AI145406NIAID NIH HHS U01 AI156923NIAID NIH HHS U01 AI156924
Abstract
PubMed holds no abstract for this paper.
Indexed as
FerroptosisUbiquinoneElectron Transport Complex IFree RadicalsLipid PeroxidationOxidation-ReductionOxidoreductasesVitamin EElectron Transport Complex Ifree radical reductaseFree RadicalsOxidoreductasesUbiquinoneVitamin Ecoenzyme Qcytochrome b5 reductaseelectron transportersferroptosisferroptosis suppressing protein 1free radical reductasephosphatidylethanoamine peroxidationvitamin E
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.