Evidence map›Paper›PMID 37154726›Full record

ArticlemSphere2023

Serum Immune Responses to Group A Streptococcal Antigens following Pharyngeal Acquisitions among Children in Cape Town, South Africa.

M Taariq Salie, Babu Muhamed, Kélin Engel, Kimona Rampersadh, Rezeen Daniels, Lwazi Mhlanti, Thomas A Penfound, Craig A Sable, Liesl J Zühlke, James B Dale and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

M Taariq SalieDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-3158-7978
Babu MuhamedDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Kélin EngelDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Kimona RampersadhDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Rezeen DanielsDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Lwazi MhlantiDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Thomas A PenfoundDepartment of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Craig A SableChildren's National Health System, Washington, DC, USA.
Liesl J ZühlkeSouth African Medical Research Council, Cape Town, South Africa.
James B DaleDepartment of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Mark E EngelDepartment of Medicine (AFROStrep Research Initiative) and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-1334-8829
University of Cape Town · ZAUniversity of Tennessee Health Science Center · USChildren's National · USSouth African Medical Research Council · ZA

Funding

Structure-Based Design of a Broadly Protective Group A Streptococcal VaccineR01AI132117 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI DALE, JAMES B. · 2017 to 2021
$3.9M
Vaccine Prevention of Group A Streptococcal InfectionsR01AI010085 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI DALE, JAMES B. · 1985 to 2016
$2.4M
Medical Research CouncilNIAID NIH HHS R01 AI010085NIAID NIH HHS R01 AI132117
6 · The paper itself

Abstract

There is limited information on the human immune response following infection with group A

Indexed as

PharyngitisStreptococcal InfectionsAnimalsAntigens, BacterialChildHumansPeptidesPharynxSouth AfricaStreptococcus pyogenesAntigens, BacterialPeptidesELISAGAS shared antigensgroup A Streptococcus (GAS)immune responselongitudinalM proteinSouth Africavaccines

Identifiers

PMID37154726
PMCPMC10286702
OpenAlexW4375954571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.