Evidence map›Paper›PMID 37154715›Full record

ArticleMicrobiology spectrum2023

CLEC18A Impairs Phagocytosis by Reducing FcγRIIA Expression and Arresting Autophagosome-Lysosome Fusion.

Tsai-Ling Liao, Yi-Ming Chen, Kuo-Tung Tang, Ying-Ying Yang, Der-Yuan Chen, Tsung-Hsien Chan, Hui-Ju Tsai, Shie-Liang Hsieh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Tsai-Ling LiaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID 0000-0001-7059-4228
Yi-Ming ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Kuo-Tung TangDivision of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan.
Ying-Ying YangDivision of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Der-Yuan ChenRheumatology and Immunology Center, China Medical University Hospital, Taichung, Taiwan.ORCID 0000-0003-1266-1423
Tsung-Hsien ChanDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Hui-Ju TsaiDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Shie-Liang HsiehGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Taichung Veterans General Hospital · TWNational Chung Hsing University · TWChina Medical University · TWNational Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed cryoglobulinemia (MC) is a hepatitis C virus (HCV)-related extrahepatic manifestation that is characterized by the abnormal presence of immune complexes (ICs). This may be due to the reduced uptake and clearance of ICs. The C-type lectin member 18A (CLEC18A) is a secretory protein that is expressed abundantly in hepatocytes. We previously observed that CLEC18A increased significantly in the phagocytes and sera of patients with HCV, particularly those with MC. Herein, we explored the biological functions of CLEC18A in the MC syndrome development of patients with HCV by using an

Indexed as

Hepatitis CHepatitis C, ChronicAntiviral AgentsAutophagosomesHepacivirusHumansLectins, C-TypeLysosomesPhagocytosisReceptors, IgGAntiviral AgentsCLEC18A protein, humanFc gamma receptor IIALectins, C-TypeReceptors, IgGC-type lectin 18AFcγRIIAhepatitis C virusmixed cryoglobulinemiaRab7

Identifiers

PMID37154715
PMCPMC10269929
OpenAlexW4375859942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.