Evidence map›Paper›PMID 37154494›Full record

ArticleAmerican journal of physiology. Cell physiology2023

SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca

Rafiquel Sarker, Ruxian Lin, Varsha Singh, Mark Donowitz, Chung-Ming Tse

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Cell physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Plant-based edible vaccines: Can cholera be the case study in Africa?Journal, genetic engineering & biotechnology · 2025
    Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rafiquel SarkerDivision of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Ruxian LinDivision of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Varsha SinghDivision of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Mark DonowitzDivision of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0003-0477-8824
Chung-Ming TseDivision of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0002-1873-2029
Johns Hopkins University · US

Funding

Project 3 - Human colonoids as a model for the pathobiology of EHECP01AI125181 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FOULKE-ABEL, JENNIFER, KAPER, JAMES B · 2016 to 2025
$18.6M
Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0M
Translational Approaches to Develop Drug Therapy for DiarrheaR24DK099803 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI DONOWITZ, MARK · 2014 to 2019
$8.9M
DIARRHEAL DISEASES: A PHYSIOLOGIC APPROACH TO TREATMENTR01DK026523 · NIDDK · TUFTS MEDICAL CENTER · PI DONOWITZ, MARK · 1986 to 2016
$7.8M
Mechanisms and Correction of Abnormal Bicarbonate Secretion by DRA in DiarrheaR01DK116352 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TSE, CHUNG-MING · 2019 to 2022
$2.2M
NIAID NIH HHS P01 AI125181NIDDK NIH HHS P30 DK089502NIDDK NIH HHS R01 DK026523NIDDK NIH HHS R01 DK116352NIDDK NIH HHS R24 DK099803
6 · The paper itself

Abstract

In polarized intestinal epithelial cells, downregulated in adenoma (DRA) is an apical Cl

Indexed as

Epithelial CellsSodium ChlorideAdenosine TriphosphateAnionsCaco-2 CellsChloride-Bicarbonate AntiportersDiarrheaEgtazic AcidHumansSodium-Hydrogen Exchanger 3Sulfate Transporters1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl esterAdenosine TriphosphateAnionsChloride-Bicarbonate AntiportersEgtazic AcidSLC26A3 protein, humanSodium ChlorideSodium-Hydrogen Exchanger 3Sulfate Transportersadenosine 5′-triphosphateCa2+cAMPDRASLC26A3synergy

Identifiers

PMID37154494
PMCPMC10243534
OpenAlexW4375865435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.