Evidence map›Paper›PMID 37153981›Full record

ArticleAllergy, asthma & immunology research2023

Global Disease Burden and Attributable Risk Factor Analysis of Asthma in 204 Countries and Territories From 1990 to 2019.

Hailing Liu, Jing Zhang, Li Liu, Guoli Lian, Ruiming Shi, Man Xu, Juan Yang, Xiaohong Liu

Open access · diamondAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Health loss and economic burden of asthma in China: a qualitative review based on existing literature.Archives of public health = Archives belges de sante publique · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hailing Liu *Department of Pediatrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0003-1094-4753
Jing Zhang *Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0002-3577-4677
Li LiuDepartment of Pediatrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0001-6064-1342
Guoli LianDepartment of Pediatrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0002-6650-5015
Ruiming ShiDepartment of Pediatrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0002-9609-6806
Man XuDepartment of Pediatrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0003-1092-8964
Juan YangDepartment of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, P. R. China.ORCID https://orcid.org/0000-0001-9965-0836
Xiaohong LiuDepartment of Pediatrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China. liuxiaoh@mail.xjtu.edu.cn.ORCID https://orcid.org/0000-0001-5583-5839
First Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

Scientific Research Foundation of The First Affiliated Hospital of Xi'an Jiaotong University 2021ZYTS-34The Scientific Research and Sharing Platform Construction Project of Shaanxi Province 2022PT-07
6 · The paper itself

Abstract

purposeAsthma is a common chronic inflammatory respiratory tract disease with high morbidity and mortality. The global trends in asthma burden remain poorly understood, and asthma incidence has increased during the worldwide coronavirus disease 2019 (COVID-19) pandemic. This study aimed to provide a comprehensive view of the global distribution of asthma burden and its attributable risk factors from 1990 to 2019.

methodsBased on the Global Burden of Disease Study 2019 Database, asthma incidence, deaths, disability-adjusted life years (DALYs), the corresponding age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), age-standardized DALY rate, and estimated annual percentage change were analyzed according to age, sex, sociodemographic index (SDI) quintiles, and locations. Risk factors contributing to asthma deaths and DALYs were also investigated.

resultsGlobally, the asthma incidence increased by 15%, but deaths and DALYs decreased. The corresponding ASIR, ASDR, and age-standardized DALY rate also decreased. The high SDI region had the highest ASIR, and the low SDI region had the highest ASDR. The ASDR and age-standardized DALY rate were negatively correlated with the SDI. The low-middle SDI region, particularly South Asia, showed the highest asthma-related deaths and DALYs. The incidence peak was under 9 years old, and more than 70% of all deaths occurred in the population over 60 years old. Smoking, occupational asthmagens, and a high body mass index were the main risk factors for asthma-related mortality and DALYs, and their distributions varied between sexes.

conclusionsGlobally, the asthma incidence has increased since 1990. The greatest asthma burden is borne by the low-middle SDI region. The 2 groups that need special attention are those under 9 years old and those over 60 years old. Targeted strategies are needed to reduce the asthma burden based on geographic and sex-age characteristics. Our findings also provide a platform for further investigation into the asthma burden in the era of COVID-19.

Indexed as

Asthmadeathdisability-adjusted life yearsglobal burden of diseaseincidencerisk factors

Identifiers

PMID37153981
PMCPMC10359648
OpenAlexW4375955201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.