Evidence map›Paper›PMID 37153928›Full record

ReviewJournal of International Society of Preventive & Community Dentistry

Role of Medicinal Herbs in Periodontal Therapy: A Systematic Review.

Mohan Kumar Pasupuleti, Raghavendra R Nagate, Saad M Alqahtani, Gautami S Penmetsa, Sruthima N V S Gottumukkala, K S V Ramesh

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07410156 (Clinical Evaluation of Microneedling Technique With Topical Application of Silymarin on Gingival Hyperpigmentation in Comparison With Diode Laser and Scalpel Methods. A Randomized Clinical Trial), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07410156 narecruitingnot on this map

Clinical Evaluation of Microneedling Technique With Topical Application of Silymarin on Gingival Hyperpigmentation in Comparison With Diode Laser and Scalpel Methods. A Randomized Clinical Trial

TypeinterventionalSponsorFayoum UniversityRan2026 to 2027Enrolled30ConditionsGingival Pigmentation, Gingival HyperpigmentaionArmsGingival Depigmentation with Conventional Method, Gingival Depigmentation with Diode Laser, Gingival Depigmentation with Microneedling and Silymarin Application
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effect ofFrontiers in pharmacology · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. In silico evaluation ofJournal of Taibah University Medical Sciences · 2026
    Article
  10. Review
  11. Role of Carvacrol in Oral Health: An Overview.Current pharmaceutical design · 2026
    Review
  12. Article
  13. Chitosan Nanoparticles Entrapping AqueousPlants (Basel, Switzerland) · 2025
    Article
  14. Article
  15. Article
  16. Proanthocyanidin B2 alleviatesCytotechnology · 2025
    Article
  17. Article
  18. Review
  19. Phytotoxic and Antifungal Effects ofPathogens (Basel, Switzerland) · 2025
    Article
  20. Bioinformation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohan Kumar PasupuletiDepartment of Periodontics and Implantology, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari, Andhra Pradesh, India.
Raghavendra R NagateDivision of Periodontics, Department of Periodontics and Community Dental Sciences (PCS), College of Dentistry, King Khalid University, Abha, Kingdom of Saudi Arabia.
Saad M AlqahtaniDivision of Periodontics, Department of Periodontics and Community Dental Sciences (PCS), College of Dentistry, King Khalid University, Abha, Kingdom of Saudi Arabia.
Gautami S PenmetsaDepartment of Periodontics and Implantology, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari, Andhra Pradesh, India.
Sruthima N V S GottumukkalaDepartment of Periodontics and Implantology, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari, Andhra Pradesh, India.
K S V RameshDepartment of Periodontics and Implantology, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari, Andhra Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims and Objectives: The use of medicinal herbs to prevent gingival and periodontal diseases has become increasingly popular due to their anti-inflammatory and antioxidant properties. This systematic review aims to provide the current literature to validate the traditional use of medicinal herbs in the management of gingival and periodontal diseases. Materials and Methods: An online literature search was conducted to identify research papers published from 2010 to 2022 in three major scientific databases, PubMed, Scopus, and Web of Science, in June 2022. Original research studies, case reports, and systematic reviews on medicinal plants' application in oral health care were selected to be included in this systematic review. Only high-quality articles identified in the quality assessment were included for evidence synthesis. Results: Initial keyword research yielded 726 free-text articles published between 2010 and 2022. Of these, 14 articles (8 research papers and 6 reviews) were included for evidence synthesis. The review's findings indicate that the antibacterial property of medicinal plants is due to their alkaline nature and prevents plaque and calculus formation by maintaining acid-alkali balance in saliva. Various parts of medicinal plants help maintain periodontal health. Conclusion: The anti-inflammatory, antioxidant, antibacterial, and astringent action of extracts obtained from various parts of medicinal plants make them effective in reducing gingival and periodontal diseases. Herbal medicine may be a viable alternative to contemporary pharmaceuticals as an adjuvant to scaling and root planning procedures.

Indexed as

Herbsmedicinal plantsperiodontal diseasephytomedicinesputative periodontal pathogens

Identifiers

PMID37153928
PMCPMC10155875

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.