Evidence map›Paper›PMID 37153746›Full record

ArticleTheranostics2023

Hypoxia Induces M2 Macrophages to Express VSIG4 and Mediate Cardiac Fibrosis After Myocardial Infarction.

Yan Wang, Yu Zhang, Jiao Li, Chaofu Li, Ranzun Zhao, Changyin Shen, Weiwei Liu, Jidong Rong, Zhenglong Wang, Junbo Ge and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yan WangDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Yu ZhangDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Jiao LiDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Chaofu LiDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Ranzun ZhaoDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Changyin ShenDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Weiwei LiuDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Jidong RongDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Zhenglong WangDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Junbo GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Bei ShiDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Zunyi Medical University · CNSoochow University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

M2 macrophage-mediated tissue repair plays an important role in acute myocardial infarction (AMI). Additionally, VSIG4, which is mainly expressed on tissue-resident and M2 macrophages, is crucial for the regulation of immune homeostasis; however, its effects on AMI remain unknown. In this study, we aimed to investigate the functional significance of VSIG4 in AMI using

Indexed as

Myocardial InfarctionAnimalsFibrosisHypoxiaMacrophagesMiceMice, Inbred C57BLMyocardiumReceptors, ComplementReceptors, ComplementVSIG4 protein, mouseCardiac fibrosisHypoxiaMacrophagesMyocardial infarctionVSIG4

Identifiers

PMID37153746
PMCPMC10157727
OpenAlexW4364321285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.