Evidence map›Paper›PMID 37153600›Full record

ArticleFrontiers in immunology2023

Regulator of G-protein signaling 1 critically supports CD8

Diego von Werdt, Bilgi Gungor, Juliana Barreto de Albuquerque, Thomas Gruber, Daniel Zysset, Cheong K C Kwong Chung, Antonia Corrêa-Ferreira, Regina Berchtold, Nicolas Page, Mirjam Schenk and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Integrative Transcriptomics and Mendelian Randomization IdentifyCurrent issues in molecular biology · 2026
    Article
  2. TScience immunology · 2025
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 3 countries.

Diego von WerdtDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Bilgi GungorDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Juliana Barreto de AlbuquerqueDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Thomas GruberDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Daniel ZyssetDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Cheong K C Kwong ChungDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Antonia Corrêa-FerreiraDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Regina BerchtoldDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Nicolas PageDepartment of Pathology, Division of Clinical Pathology, University & University Hospitals of Geneva, Geneva, Switzerland.
Mirjam SchenkDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
John H KehrlNational Institute of Allergy and Infectious Diseases, Bethesda, MD, United States.
Doron MerklerDepartment of Pathology, Division of Clinical Pathology, University & University Hospitals of Geneva, Geneva, Switzerland.
Beat A ImhofDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Jens V SteinDepartment of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
Jun AbeDepartment of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
Gleb TurchinovichDepartment of Biomedicine, and University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Daniela FinkeDepartment of Biomedicine, and University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Adrian C HaydayPeter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Nadia CorazzaDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Christoph MuellerDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
University of Bern · CHUniversity Children’s Hospital Basel · CHUniversity Hospital of Geneva · CHUniversity of Fribourg · CHNational Institute of Allergy and Infectious Diseases · USNestlé (Switzerland) · CHThe Francis Crick Institute · GB

Funding

Control Of G Protein Signaling: Role Of The RGSsZIAAI000738 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI KEHRL, JOHN H · 2009 to 2025
$15.9M
Wellcome TrustWellcome Trust 106292/Z/14/Z
6 · The paper itself

Abstract

Members of the Regulator of G-protein signaling (Rgs) family regulate the extent and timing of G protein signaling by increasing the GTPase activity of Gα protein subunits. The Rgs family member

Indexed as

CD8-Positive T-LymphocytesGTP-Binding ProteinsListeria monocytogenesAnimalsMiceProtein SubunitsT-Lymphocyte SubsetsGTP-Binding ProteinsProtein Subunitsimmunosurveillanceintestinal listeria monocytogenes infectionregulator of G-protein signaling-1T-cell differentiationTRM cells

Identifiers

PMID37153600
PMCPMC10158727
OpenAlexW4366595810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.