Evidence map›Paper›PMID 37153358›Full record

ArticleJournal of multidisciplinary healthcare2023

Profiles of Independent-Comorbidity Groups in Senior COVID-19 Patients Reveal Low Fatality Associated with Standard Care and Low-Dose Hydroxychloroquine over Antivirals.

Kamaleldin B Said, Ahmed Alsolami, Fayez Saud Alreshidi, Anas Fathuddin, Fawwaz Alshammari, Fauwaz Alrashid, Ahmed Aljadani, Rana Aboras, Fatmah Alreshidi, Mohammed H Alghozwi and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of multidisciplinary healthcare, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Kamaleldin B SaidDepartment of Pathology and Microbiology, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.ORCID 0000-0002-3749-6754
Ahmed AlsolamiDepartment of Internal Medicine, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Fayez Saud AlreshidiDeparmtent of Family, Community Medicine, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Anas FathuddinDepartment of Plastic Surgery, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Fawwaz AlshammariDepartment of Dermatology, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Fauwaz AlrashidDepartment of Surgery, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Ahmed AljadaniDepartment of Internal Medicine, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Rana AborasDeparmtent of Family, Community Medicine, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Fatmah AlreshidiDeparmtent of Family, Community Medicine, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Mohammed H AlghozwiDepartment of Pathology and Microbiology, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Suliman F AlshammariDepartment of Pathology and Microbiology, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Nawaf F AlharbiDepartment of Pathology and Microbiology, College of Medicine, University of Ha'il, Ha'il, 55476, Saudi Arabia.
Ha’il COM Research Unit Group
University of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The lack of feasible therapies and comorbidities aggravate the COVID-19 case-fatality rate (CFR). However, reports examining CFR associations with diabetes, concomitant cardiovascular diseases, chronic kidney disease, and chronic liver disease (CLD) are limited. More studies assessing hydroxychloroquine (Hcq) and antivirals are needed. Purpose: To examine associations of COVID-19 CFR in comorbid patient groups each with single comorbidities and after treatment with Hcq, favipiravir, and dexamethasone (Dex), either alone or in combination versus standard care. Methods: Using statistical analysis, we descriptively determined these associations among 750 COVID-19 patient groups during the last quarter of 2021. Results: A diabetes comorbidity (40%, n=299) showed twice the fatality (CFR 14%) of the others (CFR 7%; Conclusion: The dominance of diabetes and other comorbidities with significant association with CFR implied existence of a common virulence mechanism. The superiority of low-dose Hcq and standard care over antivirals warrants further studies.

Indexed as

comorbid COVID-19 eldersCOVID-19 medicine treatmentsCOVID-19 supportive treatmentCOVID-19 survivals and deaths

Identifiers

PMID37153358
PMCPMC10162097
OpenAlexW4367624229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.