ArticleFrontiers in physiology2023
The mushroom body development and learning ability of adult honeybees are influenced by cold exposure during their early pupal stage.
Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 14 citations in OpenAlex.
- Never underestimate honeybees: Their exceptionally diverse adaptive strategies.Journal of advanced research · 2026Review
- Selection ofInsects · 2025Article
- Biochemical and Transcriptomic Analysis Reveals Low Temperature-Driven Oxidative Stress in PupalInsects · 2025Article
- Impact of developmental temperature on neural growth, connectivity, and function.Science advances · 2025Article
- Article
- Article
- Drosophila larvae form appetitive and aversive associative memory in response to thermal conditioning.PloS one · 2024Article
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Authors and funding
12 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The honeybees are the most important pollinator in the production of crops and fresh produce. Temperature affects the survival of honeybees, and determines the quality of their development, which is of great significance for beekeeping production. Yet, little was known about how does low temperature stress during development stage cause bee death and any sub-lethal effect on subsequent. Early pupal stage is the most sensitive stage to low temperature in pupal stage. In this study, early pupal broods were exposed to 20°C for 12, 16, 24, and 48 h, followed by incubation at 35°C until emergence. We found that 48 h of low temperature duration cause 70% of individual bees to die. Although the mortality at 12 and 16 h seems not very high, the association learning ability of the surviving individuals was greatly affected. The brain slices of honeybees showed that low temperature treatment could cause the brain development of honeybees to almost stop. Gene expression profiles between low temperature treatment groups (T24, T48) and the control revealed that 1,267 and 1,174 genes were differentially expressed respectively. Functional enrichment analysis of differentially expressed genes showed that the differential expression of
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