Evidence map›Paper›PMID 37152918›Full record

ArticleJournal of vascular surgery cases and innovative techniques2023

Initial experience with a modified "candy-plug" technique for false lumen embolization in chronic type B aortic dissection.

Daniel Miles, Cassra Arbabi, Katherine McMackin, Bruce Tjaden, Sally Schonefeld, Donald Baril, NavYash Gupta, Bruce Gewertz, Ali Azizzadeh

Open access · goldAbstract read
In one paragraph

Article in Journal of vascular surgery cases and innovative techniques, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Thermal septotomy complications and management of residual septum visceral ostial occlusions.Journal of vascular surgery cases and innovative techniques · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Thoracic Endovascular Aortic Repair.Annals of vascular diseases · 2026
    Review
  6. Controversies in Chronic Aortic Dissection.Seminars in interventional radiology · 2024
    Review
  7. Article
  8. Review
  9. Candy-plug: Failure to launch.Journal of vascular surgery cases and innovative techniques · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel MilesDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Cassra ArbabiDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Katherine McMackinDivision of Vascular and Endovascular Surgery, Cooper University Hospital, Camden, NJ.
Bruce TjadenDivision of Vascular and Endovascular Surgery, Cooper University Hospital, Camden, NJ.
Sally SchonefeldDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Donald BarilDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
NavYash GuptaDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Bruce GewertzDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Ali AzizzadehDivision of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Cedars-Sinai Medical Center · USCooper University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Persistent distal false lumen (FL) perfusion after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) can lead to aneurysmal degeneration and an increased risk of rupture. We have presented our initial experience using a modified "candy-plug" (CP) technique for FL embolization. Methods: From February 2021 to July 2022, we treated six patients using the modified CP technique. All the patients had undergone prior or simultaneous TEVAR for chronic TBAD with persistent FL perfusion and aneurysm expansion. Bilateral common femoral artery access was obtained, and intravascular ultrasound was used to confirm wire access in the true lumen (TL) and FL. A conformable TAG device (W.L. Gore & Associates, Flagstaff, AZ) was used in four cases and an Excluder aortic cuff (W.L. Gore & Associates) in two cases. The device was modified by placing a constraining "napkin-ring" suture through the middle segment of the device. Femoral sheaths were placed in the TL and FL. A standard TL TEVAR extension was performed at the level of the celiac artery (zone 5). Next, the CP device was advanced and deployed in the FL, distally aligning it with the TL device. An appropriately sized Amplatzer II plug (Abbot Vascular, Santa Clara, CA) was then deployed in the constrained segment of the modified stent graft. Completion angiography was performed to confirm successful FL embolization. Results: Technical success was defined as successful deployment of the CP device in the FL. The technical success rate was 100% (six of six patients). Clinical success was defined as the cessation of aneurysm growth on follow-up computed tomography angiography. No 30-day mortality, myocardial infarction, stroke, spinal cord ischemia, access site complications, or aortic-related reinterventions occurred. Surveillance imaging at a mean follow-up of 10 months confirmed clinical success (stable aneurysm size or shrinkage) for all five patients with follow-up data available. Conclusions: The modified CP embolization technique is a promising solution for persistent distal FL perfusion after TEVAR for TBAD. Further investigation is required to determine the long-term durability of this technique as an adjunct to TEVAR to promote aortic remodeling.

Indexed as

Aortic remodelingCandy-plugFalse lumen embolizationFalse lumen perfusionTEVARType B aortic dissection

Identifiers

PMID37152918
PMCPMC10154964
OpenAlexW4311139144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.