Evidence map›Paper›PMID 37152635›Full record

ArticleAdvances in pharmacological and pharmaceutical sciences2023

Anticataract Effect of the Aqueous Extract of the Flowers of

Adwoa Frema Amanfo, Samuel Kyei, Yaw Duah Boakye, Clement Osei Akoto, Justice Kwaku Addo, Kofi Oduro Yeboah, Newman Osafo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in pharmacological and pharmaceutical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adwoa Frema AmanfoDepartment of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.ORCID https://orcid.org/0000-0002-4874-5015
Samuel KyeiDepartment of Optometry and Vision Science, University of Cape Coast, Cape Coast, Ghana.ORCID https://orcid.org/0000-0003-2568-8246
Yaw Duah BoakyeDepartment of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.ORCID https://orcid.org/0000-0002-2134-0034
Clement Osei AkotoDepartment of Chemistry, College of Science, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.ORCID https://orcid.org/0000-0003-2717-2753
Justice Kwaku AddoDepartment of Chemistry, University of Cape Coast, Cape Coast, Ghana.ORCID https://orcid.org/0000-0003-0196-2087
Kofi Oduro YeboahDepartment of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.ORCID https://orcid.org/0000-0001-7080-0730
Newman OsafoDepartment of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.ORCID https://orcid.org/0000-0001-8142-2368
Kwame Nkrumah University of Science and Technology · GHUniversity of Cape Coast · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The use of Methods: Preliminary phytochemical screening of the extract, in vitro antioxidant assays, and in vitro aldose reductase inhibitory activity were performed. For anticataract investigations of the extracts, diabetic cataract was induced by galactose administration in 3-week-old Sprague Dawley rats. The evaluation of experimentally induced age-related cataract was performed by administering sodium selenite to 10-day-old rat pups. Results: The phytochemical analysis revealed the presence of alkaloids, tannins, flavonoids, glycosides, and saponins. In vitro aldose reductase inhibitory property of the extract on rat lenses revealed that the AAE inhibited the enzyme activity with IC Conclusion: The study established the anticataract potential of the aqueous extract of flowers of

Identifiers

PMID37152635
PMCPMC10159747
OpenAlexW4367178634

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.