Evidence map›Paper›PMID 37152561›Full record

ReviewRSC advances2023

An updated review of fatty acid residue-tethered heterocyclic compounds: synthetic strategies and biological significance.

Taghreed A Majrashi, Ahmed Sabt, Hayam A Abd El Salam, Ghada H Al-Ansary, Mohamed Farouk Hamissa, Wagdy M Eldehna

Open access · goldAbstract readReview
In one paragraph

Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Investigation of Potent Anti-Drug design, development and therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Taghreed A MajrashiDepartment of Pharmacognosy, College of Pharmacy, King Khalid University Asir 61421 Saudi Arabia.
Ahmed SabtChemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre Dokki Cairo Egypt.
Hayam A Abd El SalamDepartment of Green Chemistry, National Research Center Dokki Cairo 12622 Egypt.
Ghada H Al-AnsaryDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University Cairo P.O. Box 11566 Egypt.
Mohamed Farouk HamissaMedicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618) 33 El Bohouth St., P.O. 12622, Dokki Giza Egypt mfahamissa@hotmail.com.ORCID https://orcid.org/0000-0003-0494-4255
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University Kafrelsheikh P.O. Box 33516 Egypt wagdy2000@gmail.com.ORCID https://orcid.org/0000-0001-6996-4017
National Research Centre · EGAin Shams University · EGKafrelsheikh University · EGKing Khalid University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterocyclic compounds have been featured as the key building blocks for the development of biologically active molecules. In addition to being derived from renewable raw materials, fatty acids possess a variety of biological properties. The two bioactive ingredients are being combined by many researchers to produce hybrid molecules that have a number of desirable properties. Biological activities and significance of heterocyclic derivatives of fatty acids have been demonstrated in a new class of heterocyclic compounds called heterocyclic fatty acid hybrid derivatives. The significance of heterocyclic-fatty acid hybrid derivatives has been emphasized in numerous research articles over the past few years. In this review, we emphasize the development of synthetic methods and their biological evaluation for heterocyclic fatty acid derivatives. These reports, combined with the upcoming compilation, are expected to serve as comprehensive foundations and references for synthetic, preparative, and applicable methods in medicinal chemistry.

Identifiers

PMID37152561
PMCPMC10157362
OpenAlexW4375856270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.