Evidence map›Paper›PMID 37152421›Full record

ReviewTherapeutic advances in medical oncology2023

A practical proposal on treatment sequencing of metastatic well-differentiated neuroendocrine tumours.

Marine Perrier, Jean-Yves Scoazec, Thomas Walter

Abstract readReview
In one paragraph

Review in Therapeutic advances in medical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marine PerrierUniversité Reims Champagne-Ardenne, Department of Gastroenterology and Digestive Oncology, Reims University Hospital, Reims, France.ORCID https://orcid.org/0000-0002-4528-5471
Jean-Yves ScoazecDepartment of Surgical and Molecular Pathology, Gustave Roussy, Villejuif, France.
Thomas WalterDepartment of Medical Oncology, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon 69437, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the neuroendocrine tumour (NET) characteristics, 3 to 7 different treatment options are available, corresponding to 6 to 5,040 theoretical different sequences. Even though each patient is unique and despite a large heterogeneity in NET characteristics, the present review aims to discuss the main sequences and addresses how one can propose the best sequence to treat metastatic NET (mNET) on a case-by-case basis. Each treatment must be discussed during dedicated multi-disciplinary meetings, and inclusions in clinical trials should be favoured. After a thorough characterization of patients and their mNET, and taking into account the availability of drugs, the first-line treatment should be chosen according to the treatment aim. The latter is determined based on three main topics (efficacy, safety, and patient preferences) that do not necessarily converge and must be defined

Indexed as

metastaticneuroendocrine tumoursequencestrategytreatment

Identifiers

PMID37152421
PMCPMC10155015

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.