Evidence map›Paper›PMID 37152102›Full record

ArticleDrug design, development and therapy2023

Feasibility and Safety of Remazolam versus Propofol When Inserting Laryngeal Masks Without Muscle Relaxants During Hysteroscopy.

Shan Tang, Jingxiao Lu, Cheng Xu, Lu Wei, Shenglan Mei, Rong Chen, Qing-Tao Meng

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shan TangDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Jingxiao LuDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Cheng XuDepartment of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Lu WeiDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Shenglan MeiDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Rong ChenDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Qing-Tao MengDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Wuhan University · CNRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the efficacy and safety of remazolam compared with propofol in patients who underwent laryngeal mask airway (LMA) insertion without the use of muscle relaxant agents during hysteroscopic surgery. Patients and Methods: A total of 72 patients undergoing hysteroscopy with LMA insertion were assigned to two groups. The patients in the remazolam group received 0.3 μg/kg sufentanil, 0.3 mg/kg remazolam and 1.2 mg/kg remifentanil, whereas the patients in the propofol group received 0.3 μg/kg sufentanil, 2.0 mg/kg propofol and 1.2 mg/kg remifentanil for insertion of the LMA. The primary endpoint was the summed score of the insertion conditions. The secondary endpoints included hemodynamics, the duration of induction, the duration of insertion, tidal volume, plateau pressure and adverse events. Results: No difference was identified between the propofol group and remazolam group in the median summed score [18.0 (18.0, 18.0), 18.0 (17.0, 18.0), respectively, Conclusion: Remazolam provided similar insertion conditions and better hemodynamic stability than propofol during LMA insertion without the use of muscle relaxant agents. However, a higher incidence of transient mild laryngospasm was found in the remazolam group, which should be considered.

Indexed as

Laryngeal MasksLaryngismusPropofolAnesthetics, IntravenousFeasibility StudiesFemaleHumansHysteroscopyMusclesPregnancyRemifentanilSufentanilVasodilator AgentsAnesthetics, IntravenousPropofolRemifentanilSufentanilVasodilator Agentslaryngeal mask airwaymuscle relaxantspropofolremazolam

Identifiers

PMID37152102
PMCPMC10162397
OpenAlexW4367557627

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.