Evidence map›Paper›PMID 37151889›Full record

ArticleInternational journal of biological sciences2023

Deubiquitinase USP13 regulates glycolytic reprogramming and progression in osteosarcoma by stabilizing METTL3/m

Ce Wang, Yichen Meng, Jianquan Zhao, Jun Ma, Yuechao Zhao, Rui Gao, Wei Liu, Xuhui Zhou

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. MATR3 regulates METTL3-Mediated mJournal of bioenergetics and biomembranes · 2026
    Article
  6. Article
  7. Article
  8. METTL3-mediated mMolecular cancer · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Role of the USP family in autophagy regulation and cancer progression.Apoptosis : an international journal on programmed cell death · 2025
    Review
  15. Methyltransferase-Like 3-Mediated NJournal of cellular and molecular medicine · 2025
    Review
  16. Review
  17. Review
  18. The Role of mRNA Modifications in Bone Diseases.International journal of biological sciences · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ce WangDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Yichen MengDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Jianquan ZhaoDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Jun MaDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yuechao ZhaoDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Rui GaoDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Wei LiuDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Xuhui ZhouDepartment of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Shanghai Changzheng Hospital · CNShanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reprogramming metabolism is a hallmark of cancer cells for rapid progression. However, the detailed functional role of deubiquitinating enzymes (DUBs) in tumor glycolytic reprogramming is still unknown and requires further investigation. USP13 was found to upregulate in osteosarcoma (OS) specimens and promote OS progression through regulating aerobic glycolysis. Interestingly, the m

Indexed as

Bone NeoplasmsOsteosarcomaAutophagy-Related Protein 5HumansMethyltransferasesRNA, MessengerUbiquitin-Specific ProteasesATG5 protein, humanAutophagy-Related Protein 5MethyltransferasesMETTL3 protein, humanRNA, MessengerUbiquitin-Specific ProteasesUSP13 protein, humanATG5glycolytic reprogrammingMETTL3N6-methyladenosineUSP13

Identifiers

PMID37151889
PMCPMC10158027
OpenAlexW4372046995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.