The anti-diarrheal and anti-inflammatory effects of hydroethanol extracts of ripe

B C Okeke-Nwolisa, I B Enweani-Nwokelo, P C Unekwe, I Egbuonu

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Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

B C Okeke-NwolisaDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria.

I B Enweani-NwokeloDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria.

P C UnekweDepartment of Pharmacology, Faculty of Basic Clinical Sciences, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria.

I EgbuonuDepartment of Paediatrics, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria.

Nnamdi Azikiwe University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The study aimed to determine the anti-diarrheal and anti-inflammatory activities of hydroethanolic extract of ripe Methods: Fifty male Wistar rats were divided into five groups, each for the diarrhea and inflammatory phases. Groups A and B 10 mL/kg of distilled water and 2 mL of castor oil, Groups C, D, and E received 2 mL of castor oil + extract (150, 300, and 600 mg/kg). Groups A and B received 10 mL/kg of distilled water and 0.1 mL of egg white. Groups C, D, and E received the (0.1 mL) egg white and extract (150, 300, and 600 mg/kg). Data were analyzed using SPSS (25) using ANOVA followed by Results: The acute toxicity test of HEAMP is above 5000 mg/kg and rich in flavonoids, saponins, and proteins, with carbohydrates and tannins, and glycosides at moderate levels. Steroids, alkaloids, amino acids, and triterpenoids were absent. Furthermore, 30 min after diarrhea induction, the treated groups significantly increased ( Conclusion: The HEAMP had anti-diarrheal and anti-inflammatory properties and is safe for consumption.

Indexed as

Annona muricata pulpcastor oildiarrheahydroethanolinflammationphytochemicals

Identifiers

PMID37151748

PMCPMC10155247

OpenAlexW4375855611

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-SA

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.