Evidence map›Paper›PMID 37151376›Full record

ArticleJournal of molecular liquids2023

Exploring the inhibitory potential of novel piperidine-derivatives against main protease (M

Amina Rafique, Shabbir Muhammad, Javed Iqbal, Abdullah G Al-Sehemi, Mohammad Y Alshahrani, Khurshid Ayub, Mazhar Amjad Gilani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular liquids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amina RafiqueDepartment of Chemistry, University of Agriculture, Faisalabad 38000, Pakistan.
Shabbir MuhammadDepartment of Chemistry, College of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.
Javed IqbalDepartment of Chemistry, University of Agriculture, Faisalabad 38000, Pakistan.
Abdullah G Al-SehemiDepartment of Chemistry, College of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.
Mohammad Y AlshahraniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Khurshid AyubDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, KPK 22060, Pakistan.
Mazhar Amjad GilaniDepartment of Chemistry, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current study, a hybrid computational approach consisting of different computational methods to explore the molecular electronic structures, bioactivity and therapeutic potential of piperidine compounds against SARS-CoV-2. The quantum chemical methods are used to study electronic structures of designed derivatives, molecular docking methods are used to see the most potential docking interactions for main protease (M

Indexed as

COVID-19 (6LU7)Molecular dockingMolecular dynamicsPiperidine inhibitorsQuantum computational methodsSARS-CoV-2

Identifiers

PMID37151376
PMCPMC10131809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.