ArticlePeerJ2023
Can salivary lactate be used as an anaerobic biomarker?
Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Saliva, Sweat, and Exhaled Breath as Alternative Specimens for Exercise Chemistry: Analytical Advantages, Limitations, and Comparative Progress.Biomedical chromatography : BMC · 2026Review
- Mechanistic Studies of Lactate in Heart Failure: From Metabolic Biomarker to Therapeutic Target.Reviews in cardiovascular medicine · 2026Review
- Salivary Metabolomic Signatures Associated with Sex-Specific Psychological Distress in Syrian Refugees: A Proof-of-Principle Study.Metabolites · 2026Article
- Factors Influencing Blood Lactate Concentration During Exercise: A Narrative Review With a Lactate Shuttle Perspective.Acta physiologica (Oxford, England) · 2025Review
- Salivary Biosensing Opportunities for Predicting Cognitive and Physical Human Performance.Biosensors · 2025Article
- Nitrate promotes the growth and the production of short-chain fatty acids and tryptophan from commensal anaerobeApplied and environmental microbiology · 2024Article
- Salivary diagnostics: opportunities and challenges.Theranostics · 2024Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Salivary lactate has been suggested as a non-invasive anaerobic biomarker in sports medicine for decades, yet has not been widely applied until now. This study aimed to explore possible issues related to its application and suggest directions for future method improvement. Methods: A liquid chromatography-mass spectrometry (LC-MS) method for the determination of salivary lactate was developed, validated and applied on saliva samples collected from a group of professional sprinters ( Results: The RSD of the LC-MS method was 19.70%. Salivary lactate concentration was affected by mouth rinse times before sampling (ANOVA Discussion: Salivary lactate was found to be a potential anaerobic biomarker. However, reproducible methods for sample collection and analysis, as well as more knowledge on the secretion mechanism and pattern of salivary lactate are required to make it a practical anaerobic biomarker.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.