Evidence map›Paper›PMID 37151036›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2023

Preexisting Depression and Ambulatory Status After Stroke: Florida-Puerto Rico Collaboration to Reduce Stroke Disparities.

Amy K Starosciak, Kefeng Wang, Hao Ying, Kaushik Ravipati, Samantha Spring, Carolina M Gutierrez, Hannah Gardener, David Z Rose, Dianne Foster, Chuanhui Dong and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Amy K StarosciakMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Kefeng WangMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Hao YingMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Kaushik RavipatiMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Samantha SpringMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Carolina M GutierrezMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Hannah GardenerMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
David Z RoseMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Dianne FosterMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Chuanhui DongMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Angus JamesonMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Ayham AlkhachroumMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Jose G RomanoMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Ralph L SaccoMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Tatjana RundekMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Negar AsdaghiMiami Neuroscience Institute, Baptist Health South Florida, Miami (Starosciak); University of Miami Miller School of Medicine, Miami (Wang, Ying, Spring, Gutierrez, Gardener, Dong, Alkhachroum, Romano, Sacco, Rundek, Asdaghi); Florida International University Herbert Wertheim College of Medicine, Miami (Ravipati); University of South Florida Morsani College of Medicine, Tampa (Rose); American Heart Association, Southeast Region, Atlanta (Foster); Pinellas County Emergency Medical Services, Largo, Fla. (Jameson).
Florida International University · US

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGIONR01NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 1993 to 2019
$19.2M
FAMILY STUDY OF STROKE RISK AND CAROTID ATHEROSCLEROSISR01NS040807 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BLANTON, SUSAN HALLORAN, RUNDEK, TATJANA · 2002 to 2022
$12.2M
The Data Management and BiostatisticsU54NS081763 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SACCO, RALPH L. · 2013 to 2017
$4.2M
Institutional Career Development CoreKL2TR002737 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA, SCOTT, GWENDOLYN BARBARA · 2018 to 2022
$3.6M
Disparities in Transition of Care after Acute Stroke Hospitalization: The Transition of Care Stroke Disparity Study (TCSD-S)R01MD012467 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROMANO, JOSE G, RUNDEK, TATJANA · 2017 to 2021
$3.6M
Mechanisms of Early Recurrence in Intracranial Atherosclerotic DiseaseR01NS084288 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIEBESKIND, DAVID SIGMUND, PRABHAKARAN, SHYAM · 2014 to 2018
$3.0M
Florida Regional Coordinating Center for the NINDS Stroke Trials NetworkU24NS107267 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JOSE G ROMANO · 2018 to 2026
$3.0M
Inflamm-aging of osteoprogenitor cells: A therapeutic target for improved bone healing - Resubmission - 1 - Revision - 3R01AG056169 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEUCHT, PHILIPP · 2018 to 2022
$2.4M
MUSICA - MUsic and Speech Induced Cerebral ActivationK23NS126577 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Ayham Alkhachroum · 2022 to 2026
$910k
COVERT– COvert Volitional Eye Response TestR21NS128326 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALKHACHROUM, AYHAM, CLAASSEN, JAN · 2022 to 2023
$428k
Inflamm-aging of osteoprogenitor cells: A therapeutic target for improved bone healingR56AG056169 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEUCHT, PHILIPP · 2023 to 2023
$347k
NCATS NIH HHS KL2 TR002737NCATS NIH HHS UL1 TR002736NIA NIH HHS R01 AG056169NIA NIH HHS R56 AG056169NIMHD NIH HHS R01 MD012467NINDS NIH HHS K23 NS126577NINDS NIH HHS R01 NS029993NINDS NIH HHS R01 NS040807NINDS NIH HHS R01 NS084288NINDS NIH HHS R21 NS128326NINDS NIH HHS U24 NS107267NINDS NIH HHS U54 NS081763
6 · The paper itself

Abstract

objectiveStroke is a global public health burden, and therefore it is critical to identify modifiable risk factors to reduce stroke incidence and improve outcomes. Depression is such a risk factor; however, the association between preexisting depression and stroke outcomes, such as independent ambulation, is not well studied, especially among racial-ethnic minority groups. To address this gap in the literature, effects of preexisting depression on ambulatory status at hospital discharge after stroke were evaluated among individuals participating in the racially and ethnically diverse Florida-Puerto Rico Collaboration to Reduce Stroke Disparities project.

methodsData were analyzed from a total of 42,031 ischemic stroke patients, who were independently ambulatory prior to their stroke, after discharge from 84 hospitals between 2014 and 2017. Preexisting depression was confirmed by medical history or antidepressant medication use. Multilevel multivariate logistic regression analyses were used to assess the association of preexisting depression with independent ambulation at hospital discharge. Effects of sex and race-ethnicity on this association were examined.

resultsOf 42,031 participants (mean±SD age=70.4±14.2 years; 48% were female; race-ethnicity: 16% Black, 12% Hispanic living in Florida, and 7% Hispanic living in Puerto Rico), 6,379 (15%) had preexisting depression. Compared with participants without depression, those with preexisting depression were older, were more likely to be female and non-Hispanic White, and had a greater burden of vascular risk factors or comorbid conditions. Independent ambulation at hospital discharge was less frequent among women, Black participants, and individuals with vascular risk factors or comorbid conditions. In multivariate models, preexisting depression decreased the likelihood of independent ambulation at discharge (odds ratio=0.88, 95% CI=0.81, 0.97). No interactions were found between preexisting depression and race-ethnicity or sex.

conclusionsPreexisting depression was independently associated with dependent ambulation at hospital discharge after stroke, regardless of sex and race-ethnicity. Treating depression may contribute to primary stroke prevention and could improve ambulatory status at discharge.

Indexed as

EthnicityStrokeAgedAged, 80 and overDepressionFemaleFloridaHumansMaleMiddle AgedMinority GroupsPuerto RicoRegistriesDepressionEthnicityOutcomesStroke and Other Cerebral Vascular Disease (Neuropsychiatric Aspects)

Identifiers

PMID37151036
PMCPMC10754056
OpenAlexW4375850393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.