ArticleArchives of craniofacial surgery2023
Current concepts of craniofacial fibrous dysplasia: pathophysiology and treatment.
Article in Archives of craniofacial surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Fibrous dysplasia in a patient with Carney complex.Hormones (Athens, Greece) · 2026Review
- In vitro characterization of osteoblasts from craniofacial fibrous dysplasia of bone and their impact on bone homeostasis.Orphanet journal of rare diseases · 2026Article
- Fibrous dysplasia of the jaws: four cases with conservative and resective surgical management.Case reports in plastic surgery & hand surgery · 2026Article
- Fibrous Dysplasia Developed at the Site of a Previous Central Giant Cell Granuloma in a Middle-Aged Patient: A Case Report.Case reports in dentistry · 2026Article
- Benign fibro-osseous lesions of the cranio-maxillofacial bones: an updated review with special emphasis on molecular pathogenesis.Journal of bone and mineral metabolism · 2026Review
- Craniofacial fibrous dysplasia: a challenge for general dental practitioners.British dental journal · 2025Article
- Integration of Clinical, Radiographic, Histologic, and Molecular Findings to Diagnose Craniofacial Fibrous Dysplasia.The Journal of craniofacial surgery · 2025Article
- Application of Augmented Reality Navigation in Craniofacial Surgery for Fibrous Dysplasia.Journal of neurological surgery reports · 2025Article
- Two-stage surgical strategy for extensive craniofacial fibrous dysplasia with cerebral compression.Acta neurochirurgica · 2025Article
- Surgical management of an extensive nasal mass in an adolescent: insights from diagnostic imaging and histopathology.Journal of surgical case reports · 2025Article
- Fibrous Dysplasia of the Ethmoid Bone Diagnosed in a 10-Year-Old Patient.Medicina (Kaunas, Lithuania) · 2024Article
- Malignant sarcomatous transformation of calvarial fibrous dysplasia: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- A novel technique for skull base reconstruction in craniofacial fibrous dysplasia surgery using three-dimensional printing and a dental alginate mold: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- An Unusual Case of Fibrous Dysplasia, Temporomandibular Joint Ankylosis, and Eagle's Syndrome.Cureus · 2024Article
- Fibrous dysplasia of paranasal sinuses with anterior skull-base extension presenting with pneumocephalus; a case report.Heliyon · 2024Article
- Isolated Fibrous Dysplasia of the Bilateral Nasal Bones: Complex Management of the Bony Vault.Plastic and reconstructive surgery. Global open · 2024Article
- Article
- Surgical management of severe cherubism persisting into early adulthood: a case report and literature review.Archives of craniofacial surgery · 2024Article
- Alveolar Bone Box Ostectomy Grafted with Particulate Bone Substitute with Subsequent Dental Implant Placement in a Case of Craniofacial Fibrous Dysplasia Involving the Posterior Maxilla: Case Report and Literature Review.Journal of clinical medicine · 2023Article
- Aneurysmal bone cyst arising from the surgically removed craniofacial fibrous dysplasia in the long-term follow-up: a case report.Archives of craniofacial surgery · 2023Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
Fibrous dysplasia is an uncommon genetic disorder in which bone is replaced by immature bone and fibrous tissue, manifesting as slowgrowing lesions. Sporadic post-zygotic activating mutations in GNAS gene result in dysregulated GαS-protein signaling and elevation of cyclic adenosine monophosphate in affected tissues. This condition has a broad clinical spectrum, ranging from insignificant solitary lesions to severe disease. The craniofacial area is the most common site of fibrous dysplasia, and nine out of 10 patients with fibrous dysplasia affecting the craniofacial bones present before the age of 5. Surgery is the mainstay of treatment, but the technique varies according to the location and severity of the lesion and associated symptoms. The timing and indications of surgery should be carefully chosen with multidisciplinary consultations and a patient-specific approach.
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