Evidence map›Paper›PMID 37150279›Full record

ArticleActa biomaterialia2023

Cells resident to precision templated 40-µm pore scaffolds generate small extracellular vesicles that affect CD4

T F Hady, B Hwang, R L Waworuntu, B D Ratner, J D Bryers

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biomaterialia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

T F HadyDepartment of Bioengineering, University of Washington, Seattle, WA 98105, USA.
B HwangCenter for Lung Biology, Department of Surgery, University of Washington Seattle, WA 98109, USA.
R L WaworuntuCenter for Lung Biology, Department of Surgery, University of Washington Seattle, WA 98109, USA.
B D RatnerDepartment of Bioengineering, University of Washington, Seattle, WA 98105, USA.
J D BryersDepartment of Bioengineering, University of Washington, Seattle, WA 98105, USA. Electronic address: jbryers@uw.edu.
University of Washington · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
Periodontal Biomaterials with BITE (Biofilm Immunity with Tissue Engineering)R01DE018701 · NIDCR · UNIVERSITY OF WASHINGTON · PI BRYERS, JAMES D. · 2008 to 2019
$5.0M
Tissue Regeneration by Engineered Extracellular VesiclesR01GM128991 · NIGMS · UNIVERSITY OF WASHINGTON · PI BRYERS, JAMES D. · 2019 to 2022
$1.9M
NIDCR NIH HHS R01 DE018701NIDDK NIH HHS P30 DK017047NIGMS NIH HHS R01 GM128991
6 · The paper itself

Abstract

Precision porous templated scaffolds (PTS) are a hydrogel construct of uniformly sized interconnected spherical pores that induce a pro-healing response (reducing the foreign body reaction, FBR) exclusively when the pores are 30-40µm in diameter. Our previous work demonstrated the necessity of T

Indexed as

Extracellular VesiclesToll-Like Receptor 4AnimalsCD4-Positive T-LymphocytesMiceMyeloid Differentiation Factor 88PhenotypeProteomicsSignal TransductionMyeloid Differentiation Factor 88Toll-Like Receptor 4Porous biomaterialPro-healingsEV signalingT cellTLR4

Identifiers

PMID37150279
PMCPMC10330460
OpenAlexW4372194298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.