Evidence map›Paper›PMID 37149758›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

Calcium transients in nNOS neurons underlie distinct phases of the neurovascular response to barrel cortex activation in awake mice.

Sung Ji Ahn, Antoine Anfray, Josef Anrather, Costantino Iadecola

Open access · greenAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
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  4. nNOS-expressing neurons in the mPFC mediate depression-related behaviors in mice through pPVT-mPFC projections.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  5. Article
  6. Type-I nNOS neurons orchestrate cortical neural activity and vasomotion.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sung Ji AhnFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Antoine AnfrayFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Josef AnratherFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Costantino IadecolaFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
MIND Research Institute · USWeill Cornell Medicine · US

Funding

Overexpression of the amyloid precursor protein and cerebrovascular regulationR01NS037853 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Costantino Iadecola · 1998 to 2026
$10.6M
ApoE4, Neurovascular Injury and Cognitive ImpairmentR01NS126467 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Costantino Iadecola · 2022 to 2026
$4.1M
Hypertension and neurovascular dysfunctionR37NS089323 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IADECOLA, COSTANTINO · 2015 to 2021
$3.1M
High-speed imaging of cortical and white matter microvascular flow in AD/ADRD modelsRF1NS128947 · NINDS · CORNELL UNIVERSITY · PI IADECOLA, COSTANTINO, SCHAFFER, CHRIS B · 2022 to 2022
$2.3M
High-Speed Imaging of Cortical and White Matter Microvascular Flow in AD/ADRD ModelsR01NS128947 · NINDS · CORNELL UNIVERSITY · PI Costantino Iadecola, CHRIS B SCHAFFER · 2025 to 2026
$1.6M
NINDS NIH HHS R01 NS037853NINDS NIH HHS R01 NS126467NINDS NIH HHS R01 NS128947NINDS NIH HHS R37 NS089323NINDS NIH HHS RF1 NS128947
6 · The paper itself

Abstract

Neuronal nitric oxide (NO) synthase (nNOS), a Ca

Indexed as

CalciumNeurovascular CouplingNitric Oxide Synthase Type IAnimalsCerebral CortexMiceNeuronsNitric OxideWakefulnessCalciumNitric OxideNitric Oxide Synthase Type I2-photon microscopyFunctional hyperemiaGCaMP7fneurovascular couplingnitric oxide

Identifiers

PMID37149758
PMCPMC10581240
OpenAlexW4375846993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.