Evidence map›Paper›PMID 37149149›Full record

ArticleJournal of substance use and addiction treatment2023

Perspectives on and experiences of emergency department-initiated buprenorphine among clinical pharmacists: A multi-site qualitative study.

Marissa Justen, E Jennifer Edelman, Marek Chawarski, Edouard Coupet, Ethan Cowan, Michael Lyons, Patricia Owens, Shara Martel, Lynne Richardson, Richard Rothman and 6 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03023930 (Opioid Use Disorder in the Emergency Department), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03023930 nacompletednot on this map

Opioid Use Disorder in the Emergency Department: Clinical Trials Network-0069

TypeinterventionalSponsorYale UniversityRan2017 to 2022Enrolled1,731ConditionsOpioid Use DisorderArmsStandard Dissemination Practice, Implementation Facilitation (IF)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Marissa JustenYale School of Medicine, 333 Cedar St, New Haven, CT 06510, United States of America. Electronic address: Marissa.justen@yale.edu.
E Jennifer EdelmanYale School of Medicine, Department of Internal Medicine, Edward S. Harkness, Building A, 4th floor 367 Cedar Street, New Haven, CT 06510, United States of America.
Marek ChawarskiYale School of Medicine, Department of Psychiatry, 300 George St #901, New Haven, CT 06511, United States of America.
Edouard CoupetYale School of Medicine, Department of Emergency Medicine, 464 Congress Ave, Suite 260, New Haven, CT 06519, United States of America.
Ethan CowanIcahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, United States of America.
Michael LyonsUniversity of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH 45267, United States of America.
Patricia OwensYale School of Medicine, Department of Emergency Medicine, 464 Congress Ave, Suite 260, New Haven, CT 06519, United States of America.
Shara MartelYale School of Medicine, Department of Emergency Medicine, 464 Congress Ave, Suite 260, New Haven, CT 06519, United States of America.
Lynne RichardsonIcahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, United States of America.
Richard RothmanJohn Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, United States of America.
Lauren WhitesideUniversity of Washington School of Medicine, 1959 NE Pacific St, Seattle, WA 98195, United States of America.
Patrick G O'ConnorYale School of Medicine, Department of Internal Medicine, Edward S. Harkness, Building A, 4th floor 367 Cedar Street, New Haven, CT 06510, United States of America.
Evan ZahnYale New Haven Hospital, 20 York Street, New Haven, CT 06510, United States of America.
Gail D'OnofrioYale School of Medicine, Department of Emergency Medicine, 464 Congress Ave, Suite 260, New Haven, CT 06519, United States of America.
David A FiellinYale School of Medicine, Department of Internal Medicine, Edward S. Harkness, Building A, 4th floor 367 Cedar Street, New Haven, CT 06510, United States of America; Yale School of Medicine, Department of Emergency Medicine, 464 Congress Ave, Suite 260, New Haven, CT 06519, United States of America.
Kathryn F HawkYale School of Medicine, Department of Emergency Medicine, 464 Congress Ave, Suite 260, New Haven, CT 06519, United States of America.
Yale University · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USUniversity of Cincinnati Medical Center · USUniversity of Washington · USYale New Haven Hospital · US

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
NIDA NIH HHS UG1 DA015831
6 · The paper itself

Abstract

introductionClinical pharmacists are well positioned to enhance efforts to promote emergency department (ED)-initiated buprenorphine to treat opioid use disorder (OUD). Among clinical pharmacists in urban EDs, we sought to characterize barriers and facilitators for ED-initiated buprenorphine to inform future implementation efforts and enhance access to this highly effective OUD treatment.

methodsThis study was conducted as a part of Project ED Health (CTN-0069, NCT03023930), a multisite effectiveness-implementation study aimed at promoting ED-initiated buprenorphine that was conducted between April 2017 and July 2020. Data collection and analysis were grounded in the Promoting Action on Research Implementation in Health Services (PARIHS) framework to assess perspectives on the relationship between 3 elements: evidence for buprenorphine, the ED context, and facilitation needs to promote ED-initiated buprenorphine. The study used an iterative coding process to identify overlapping themes within these 3 domains.

resultsThe study conducted eight focus groups/interviews across four geographically disparate EDs with 15 pharmacist participants. We identified six themes. Themes related to evidence included (1) varied levels of comfort and experience among pharmacists with ED-initiated buprenorphine that increased over time and (2) a perception that patients with OUD have unique challenges that require guidance to optimize ED care. With regards to context, clinical pharmacists identified: (3) their ability to clarify scope of ED care in the context of unique pharmacology, formulations, and regulations of buprenorphine to ED staff, and that (4) their presence promotes successful program implementation and quality improvement. Participants identified facilitation needs including: (5) training to promote practice change and (6) ways to leverage already existing pharmacy resources outside of the ED.

conclusionClinical pharmacists play a unique and critical role in the efforts to promote ED-initiated buprenorphine. We identified 6 themes that can inform pharmacist-specific interventions that could aid in the successful implementation of this practice.

Indexed as

BuprenorphineOpioid-Related DisordersEmergency Service, HospitalHumansOpiate Substitution TreatmentPharmacistsBuprenorphineBuprenorphineEmergency departmentOpioid use disorderPharmacist

Identifiers

PMID37149149
PMCPMC11654915
OpenAlexW4368348078

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.