Evidence map›Paper›PMID 37148961›Full record

ArticleBiological psychology2023

Is there a cost to caring? Dispositional affective empathy interacts with depressive symptoms to predict higher C-reactive protein 8 years later.

Erika M Manczak

Open access · greenAbstract read
In one paragraph

Article in Biological psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Erika M ManczakDepartment of Psychology, University of Denver, USA. Electronic address: Erika.Manczak@du.edu.
University of Denver · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VII Core ProjectU01AG071448 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Allison E Aiello, Lauren M Gaydosh · 2021 to 2026
$40.2M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectU01AG071450 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AIELLO, ALLISON E, HUMMER, ROBERT A · 2021 to 2025
$16.2M
Inflammatory trajectories across pregnancy: Investigating novel markers of risk for postpartum depressionR21MH124026 · NIMH · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DAVIS, ELYSIA POGGI, HANKIN, BENJAMIN L · 2021 to 2022
$426k
Air pollution exposure and emerging depression risk: Testing the role of peripheral inflammatory cytokines during adolescenceR21ES034599 · NIEHS · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI MANCZAK, ERIKA M · 2022 to 2023
$425k
NIA NIH HHS U01 AG071448NIA NIH HHS U01 AG071450NICHD NIH HHS P01 HD031921NIEHS NIH HHS R21 ES034599NIMH NIH HHS R21 MH124026
6 · The paper itself

Abstract

Affective empathy, including the tendency to vicariously experience the emotions of others, is a highly-valued prosocial trait, but has been previously found to be associated with higher chronic inflammation cross-sectionally and to interact with the levels of depressive symptoms in important social partners. The current study utilized prospective longitudinal data from a nationally representative study of adults in the United States to assess whether dispositional affective empathy interacted with one's own depressive symptoms to predict C-reactive protein (CRP) approximately eight years later. Results revealed that higher ratings of empathy predicted higher CRP, but only among individuals with lower levels of depressive symptoms. Higher depressive symptoms related to greater inflammation regardless of dispositional empathy and perceived stress did not account for observed associations. Taken together, these findings suggest that vicariously experiencing others' emotions may come at a biological cost, which, if sustained, may place individuals at greater risk for inflammatory diseases.

Indexed as

C-Reactive ProteinEmpathyAdultDepressionEmotionsHumansInflammationProspective StudiesReceptors, ImmunologicC-Reactive ProteinCRP protein, humanReceptors, ImmunologicDepressive symptomsEmpathyInflammationMidlifeVicarious emotion

Identifiers

PMID37148961
PMCPMC10330800
OpenAlexW4368341062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.