Evidence map›Paper›PMID 37148658›Full record

ArticleNeoplasia (New York, N.Y.)2023

Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells.

Agata Sofia Assuncao Carreira, Silvia Ravera, Chiara Zucal, Natthakan Thongon, Irene Caffa, Cecilia Astigiano, Nadia Bertola, Arianna Buongiorno, Michela Roccuzzo, Alessandra Bisio and 4 more

Open access · goldAbstract read
In one paragraph

Article in Neoplasia (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  11. Mechanisms of resistance to NAMPT inhibitors in cancer.Cancer drug resistance (Alhambra, Calif.) · 2025
    Review
  12. Article
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  14. Article
  15. PARP-1 negatively regulates nucleolar protein pool and mitochondrial activity: a cell protective mechanism.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Agata Sofia Assuncao CarreiraDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: agata.carreira@unitn.it.
Silvia RaveraDepartment of Experimental Medicine, University of Genoa, Genoa, Italy; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; Italian Institute for Genomic Medicine (IIGM), Candiolo, Italy. Electronic address: silvia.ravera@unige.it.
Chiara ZucalDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: chiara.zucal@unitn.it.
Natthakan ThongonDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; Italian Institute for Genomic Medicine (IIGM), Candiolo, Italy. Electronic address: th.natthakan@gmail.com.
Irene CaffaDepartment of Internal Medicine, University of Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. Electronic address: Irene.Caffa@unige.it.
Cecilia AstigianoDepartment of Experimental Medicine, University of Genoa, Genoa, Italy. Electronic address: cecilia.astigiano@gmail.com.
Nadia BertolaDepartment of Experimental Medicine, University of Genoa, Genoa, Italy. Electronic address: nadia.bertola@gmail.com.
Arianna BuongiornoDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: aribuongi00@gmail.com.
Michela RoccuzzoAdvanced Imaging Core Facility, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: michela.rocuzzo@unitn.it.
Alessandra BisioDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: alessandra.bisio@unitn.it.
Barbara PardiniCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; Italian Institute for Genomic Medicine (IIGM), Candiolo, Italy. Electronic address: barbara.pardini@iigm.it.
Alessio NencioniDepartment of Internal Medicine, University of Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. Electronic address: alessio.nencioni@unige.it.
Santina BruzzoneDepartment of Experimental Medicine, University of Genoa, Genoa, Italy. Electronic address: santina.bruzzone@unige.it.
Alessandro ProvenzaniDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: alessandro.provenzani@unitn.it.
University of Trento · ITUniversity of Genoa · ITItalian institute for Genomic Medicine · ITOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide phosphoribosyltransferase (NAMPT) is a key metabolic enzyme in NAD

Indexed as

NADTriple Negative Breast NeoplasmsCell Line, TumorCytokinesHumansMitochondriaNicotinamide PhosphoribosyltransferasePhosphotransferases (Alcohol Group Acceptor)CytokinesNADNicotinamide PhosphoribosyltransferaseNMRK1 protein, humanPhosphotransferases (Alcohol Group Acceptor)Drug resistanceFK866Metabolic adaptationMitochondrial fitnessMPC2NAMPT

Identifiers

PMID37148658
PMCPMC10192916
OpenAlexW4368353671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.