Evidence map›Paper›PMID 37148613›Full record

ArticleClinical biomechanics (Bristol, Avon)2023

Knee kinetics and the medial femoral cartilage cross-sectional area response to loading in indviduals with anterior cruciate ligament reconstruction.

Elizabeth Bjornsen, Hope Davis-Wilson, Alyssa Evans-Picket, W Zachary Horton, Caroline Lisee, Amanda E Munsch, Daniel Nissman, J Troy Blackburn, Jason R Franz, Brian Pietrosimone

Open access · greenAbstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Gait Biomechanical Profiles Following Anterior Cruciate Ligament Reconstruction in Sexually-Immature Pediatrics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Elizabeth BjornsenHuman Movement Science Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: ebjornse@email.unc.edu.
Hope Davis-WilsonUniversity of Colorado Anschutz Medical Campus, Aurora, CO, United States. Electronic address: hope.davis-wilson@cuanschutz.edu.
Alyssa Evans-PicketHuman Movement Science Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: alyssa7evans@unc.edu.
W Zachary HortonDepartment of Statistics, University of California, Santa Cruz, CA, United States. Electronic address: whorton@ucsc.edu.
Caroline LiseeDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: liseecar@email.unc.edu.
Amanda E MunschJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill and Raleigh, NC, United States. Electronic address: aemunsch@live.unc.edu.
Daniel NissmanDepartment of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: daniel_nissman@med.unc.edu.
J Troy BlackburnDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: troyb@email.unc.edu.
Jason R FranzJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill and Raleigh, NC, United States. Electronic address: jrfranz@email.unc.edu.
Brian PietrosimoneDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: brian@unc.edu.
University of North Carolina at Chapel Hill · USNorth Carolina State University · USUniversity of California, Santa Cruz · USUniversity of Colorado Anschutz Medical Campus · US

Funding

In vivo Manipulation of Mechanical Loading: Using Real-time Biofeedback to Strategically Understand the Acute Biomechanical, Biochemical and Structural Changes Induced by Lower Extremity LoadingR21AR074094 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRANZ, JASON R, PIETROSIMONE, BRIAN · 2018 to 2019
$357k
Posttraumatic Osteoarthritis: Establishing a Comprehensive Evaluation StrategyR03AR066840 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PIETROSIMONE, BRIAN · 2015 to 2016
$152k
NIAMS NIH HHS R03 AR066840NIAMS NIH HHS R21 AR074094
6 · The paper itself

Abstract

backgroundUltrasonography is capable of detecting morphological changes in femoral articular cartilage cross-sectional area in response to an acute bout of walking; yet, the response of femoral cartilage cross-sectional area varies between individuals. It is hypothesized that differences in joint kinetics may influence the response of cartilage to a standardized walking protocol. Therefore, the study purpose was to compare internal knee abduction and extension moments between individuals with anterior cruciate ligament reconstruction who demonstrate an acute increase, decrease, or unchanged medial femoral cross-sectional area response following 3000 steps.

methodsThe medial femoral cartilage in the anterior cruciate ligament reconstructed limb was assessed with ultrasonography before and immediately following 3000 steps of treadmill walking. Knee joint moments were calculated in the anterior cruciate ligament reconstructed limb and compared between groups throughout the stance phase of gait using linear regression and functional, mixed effects waveform analyses.

findingsNo associations between peak knee joint moments and the cross-sectional area response were observed. The group that demonstrated an acute cross-sectional area increase exhibited 1) lower knee abduction moments in early stance in comparison to the group that exhibited a decreased cross-sectional area response; and 2) greater knee extension moments in early stance in comparison to the group with an unchanged cross-sectional area response.

interpretationThe propensity of femoral cartilage to acutely increase cross-sectional area in response to walking is consistent with less-dynamic knee abduction and knee extension moment profiles.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionCartilage, ArticularOsteoarthritis, KneeBiomechanical PhenomenaGaitHumansKnee JointLower ExtremityACL reconstructionCartilage cross-sectional areaKnee abduction momentKnee extension momentUltrasound

Identifiers

PMID37148613
PMCPMC10278237
OpenAlexW4367397254

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.