Evidence map›Paper›PMID 37148375›Full record

ArticleThe ultrasound journal2023

Airway ultrasound to detect subglottic secretion above endotracheal tube cuff.

Osman Adi, Chan Pei Fong, Roslanuddin Mohd Sallehuddin, Azma Haryaty Ahmad, Kok Meng Sum, Zulrushdi Md Yusof, Gabriele Via, Guido Tavazzi

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The ultrasound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04739878 (Prospective Study On Novel Usage of Airway Ultrasound To Detect Subglottic Secretion Above Endotracheal Tube), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04739878 nacompletednot on this map

Prospective Study On Novel Usage of Airway Ultrasound To Detect Subglottic Secretion Above Endotracheal Tube(ETT) Cuff

TypeinterventionalSponsorHospital Raja Permaisuri BainunRan2021 to 2022Enrolled50ConditionsVentilator Associated PneumoniaArmsAirway Ultrasound
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Microbiological Concordance of Subglottic Secretion and Tracheal Aspirate Cultures of Critically Ill Patients with Invasive Airway Devices: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Osman AdiResuscitation and Emergency Critical Care Unit (RECCU), Trauma and Emergency Department, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia. osman.adi@gmail.com.ORCID http://orcid.org/0000-0003-4932-8907
Chan Pei FongResuscitation and Emergency Critical Care Unit (RECCU), Trauma and Emergency Department, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia.
Roslanuddin Mohd SallehuddinTrauma and Emergency Department, Hospital Sultanah Bahiyah, Alor Star, Kedah, Malaysia.
Azma Haryaty AhmadResuscitation and Emergency Critical Care Unit (RECCU), Trauma and Emergency Department, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia.
Kok Meng SumDepartment of Anesthesiology and Intensive Care, Beacon Hospital, No. 1, Jalan 215, Off Jalan Templer, Section 51, 46050, Petaling Jaya, Selangor, Malaysia.
Zulrushdi Md YusofDepartment of Radiology, Raja Permaisuri Bainun Hospital, Jalan Raja Ashman (Jalan Hospital), Ipoh, Perak, Malaysia.
Gabriele ViaCardiac Anesthesia and Intensive Care - Cardiocentro Ticino, Lugano, Switzerland.
Guido TavazziDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, DEA Piano-1, Fondazione IRCCS Policlinico S. Matteo, Viale Golgi 19, 27100, Pavia, Italy.
Institut Penyelidikan Veterinar · MYEpatocentro Ticino · CHHospital Sultanah Bahiyah · MYUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubglottic secretion had been proven as one of the causes of microaspiration and increased risk of ventilator-associated pneumonia (VAP). The role of ultrasound to detect subglottic secretion has not yet been established. PURPOSE: The purpose of this study is to determine the sensitivity and specificity of upper airway ultrasound (US) in the detection of subglottic secretions as compared to computed tomography (CT) scanning. MATERIAL AND

methodsA prospective observational study was carried out in adult trauma patients requiring mechanical ventilation and cervical CT scan. All patients had an endotracheal tube cuff-pressure maintained between 20 and 30 cm H

resultsFifty participants were consecutively included. Subglottic secretions were detected in 31 patients using upper airway US. The sensitivity and specificity of upper airway US in detecting subglottic secretion were 96.7% and 90%, respectively (PPV 93.5%, NPV 94.7%). 18 (58%) patients with subglottic secretions developed VAP during their ICU stay (p = 0.01). The area under the receiver operating curve (AUROC) was 0.977 (95% CI 0.936-1.00).

conclusionsUpper airway US is a useful tool for detecting subglottic secretions with high sensitivity and specificity. CLINICAL IMPLICATIONS: This study shows: 1. Upper airway US may aid in detecting subglottic secretions, which are linked to VAP. 2. Detecting subglottic secretions at the bedside aids in determining the best frequency of subglottic aspiration to clean the subglottic trachea. 3. Upper airway US may also aid in detecting the correct ETT position. Trial registration Clinicaltrials.gov. CLINICALTRIALS: gov identifier NCT04739878 Date of registration 2nd May 2021 URL of trial registry record https://clinicaltrials.gov/ct2/show/NCT04739878 .

Indexed as

Focused airway ultrasoundMicroaspirationPoint-of-care ultrasoundSubglottic secretionVentilator-associated pneumonia prevention

Identifiers

PMID37148375
PMCPMC10164205
OpenAlexW4372355047

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.