Evidence map›Paper›PMID 37148202›Full record

ArticleFamily practice2023

Are insect bites responsible for the rise in summer flucloxacillin prescribing in United Kingdom general practices?

Jane Wilcock, Kamila Hawthorne, Joanne Reeve, Clare Etherington, Katharine Alsop, Joanna Bircher, Douglas McKechnie, Stephen Granier, Daniel Newport, Simon Wright and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Family practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Jane WilcockGP Silverdale Medical Practice, Silverdale Medical Practice, Salford, United Kingdom.ORCID 0000-0003-0086-4688
Kamila HawthorneProfessor, Academic Office-312 Second Floor Grove Building Singleton Campus, Swansea University Medical School, Wales, United Kingdom.
Joanne ReeveProfessor, Hull York Medical School, Academy of Primary Care, United Kingdom.ORCID 0000-0002-3184-7955
Clare EtheringtonGP, Ridgeway Surgery, Harrow, London, United Kingdom.
Katharine AlsopGP, Nightingale Valley Practice, Brislington, Bristol, United Kingdom.
Joanna BircherGP, Lockside Medical Centre, Stalybridge, Tameside, United Kingdom.
Douglas McKechnieGP, University College London, Research Department of Primary Care and Population Health; Holborn Medical Centre, London, United Kingdom.
Stephen GranierGP, Whiteladies Medical Group, Whatley Road, Clifton, Bristol, United Kingdom.
Daniel NewportMedicine Trainee, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Simon WrightGP, Walkden Medical Practice, Salford, United Kingdom.
James LarcombeGP, Sedgefield, Co Durham, United Kingdom.
Chinonso NdukaubaGP, Whiteladies Medical Group, Whiteladies, Whatley Road, Clifton, Bristol, United Kingdom.
Nitharnie AnastasiusGP Ridgeway Surgery, Harrow, London, United Kingdom.
Capricorn Automotive (United Kingdom) · GBFlorence Nightingale Foundation · GBHull York Medical School · GBRowden Medical Partnership · GBSedgefield Community Hospital · GBSwansea University · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsect bite inflammation may mimic cellulitis and promote unnecessary antibiotic usage, contributing to antimicrobial resistance in primary care. We wondered how general practice clinicians assess and manage insect bites, diagnose cellulitis, and prescribe antibiotics.

methodThis is a Quality Improvement study in which 10 general practices in England and Wales investigated patients attending for the first time with insect bites between April and September 2021 to their practices. Mode of consultation, presentation, management plan, and reattendance or referral were noted. Total practice flucloxacillin prescribing was compared to that for insect bites.

resultsA combined list size of 161,346 yielded 355 insect bite consultations. Nearly two-thirds were female, ages 3-89 years old, with July as the peak month and a mean weekly incidence of 8 per 100,000. GPs still undertook most consultations; most were phone consultations, with photo support for over half. Over 40% presented between days 1 and 3 and common symptoms were redness, itchness, pain, and heat. Vital sign recording was not common, and only 22% of patients were already taking an antihistamine despite 45% complaining of itch. Antibiotics were prescribed to nearly three-quarters of the patients, mainly orally and mostly as flucloxacillin. Reattendance occurred for 12% and referral to hospital for 2%. Flucloxacillin for insect bites contributed a mean of 5.1% of total practice flucloxacillin prescriptions, with a peak of 10.7% in July.

conclusionsAntibiotics are likely to be overused in our insect bite practice and patients could make more use of antihistamines for itch before consulting.

Indexed as

General PracticeInsect Bites and StingsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsCellulitisChildChild, PreschoolFemaleFloxacillinHumansMaleMiddle AgedPractice Patterns, Physicians'Anti-Bacterial AgentsFloxacillinantibioticsdermatologyinfectious diseasespractice managementvenomous bites and stings

Identifiers

PMID37148202
PMCPMC10745258
OpenAlexW4372351687

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.