ArticleInternational journal of impotence research2023
Intermediate-term results of TachoSil grafting to correct residual curvature during inflatable penile prosthesis implantation in patients with Peyronie's disease.
Article in International journal of impotence research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Perioperative therapies and techniques to enhance penile dimensional and functional outcomes following inflatable penile prosthesis implantation: a contemporary 10-year systematic review.Asian journal of andrology · 2026Pooled it
- SAPOC technique for length restoration in complex Peyronie's disease and erectile dysfunction at the time of penile prosthesis placement.International journal of impotence research · 2026Article
- Long-term histological and hemodynamic findings of repairing penile tunica albuginea defects with collagen fleece in dogs.International journal of impotence research · 2025Article
- Simultaneous penile prosthesis placement and collagen fleece (TachoSil) grafting. Where do we stand in 2024?International journal of impotence research · 2025Review
- Response to the Commentary on "Intermediate-term results of TachoSil grafting to correct residual curvature during inflatable penile prosthesis implantation in patients with Peyronie's disease".International journal of impotence research · 2025Article
- Perioperative outcomes of penile prosthesis implantation in Germany: results from the GRAND study.International journal of impotence research · 2024Article
- Commentary on "Intermediate-term results of TachoSil grafting to correct residual curvature during inflatable penile prosthesis implantation in patients with Peyronie's disease."International journal of impotence research · 2024Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
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Abstract
Grafting techniques may be mandatory to improve residual penile curvature during inflatable penile prosthesis (IPP) implantation in Peyronie's disease patients. We aimed to report the intermediate-term outcomes of grafting with TachoSil (Corza Health, San Diego, USA) in patients with severe erectile dysfunction and concomitant complex Peyronie's disease through a prospective cohort study. We included 25 patients that underwent the PICS (penile implant in combination with Sealing) technique from 2017 to 2020 and were evaluated 24 months after surgery. Their mean age was 61.8 ± 8.7 years. Total straightness of the penis was achieved in 21 cases, while 4 (16%) patients presented a residual penile curvature of less than 15°. The mean penile length increased significantly (15 ± 1.2 to 16.4 ± 1.6 cm, p < 0.001). No intraoperative complications occurred, while, postoperatively, two patients developed fever and three scrotal hematoma, which resolved spontaneously. At three and six weeks, as well as at 24 months after surgery, no further complications occurred, and no cases of penile glans hyposensitivity were observed. At the 24-month follow-up evaluation, the 5-item score of the International Index of Erectile Function was 23.7 ± 1.4 (range: 20.5-25) and all patients responded positively to questions 2 and 3 of the sexual encounter profile questionnaire (p < 0.001 for all outcomes compared to baseline). Accordingly, the Erectile Dysfunction Inventory of Treatment Satisfaction score improved from 45.8 ± 6 at baseline to 25.6 ± 4.6 at 24 months, p < 0.001. Grafting with TachoSil to improve residual penile curvature during IPP is a safe and effective procedure. Nevertheless, careful patient selection and counseling, surgeon's experience with the technique, and strict postoperative penile rehabilitation are the main factors for treatment success and high satisfaction rates.
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