Evidence map›Paper›PMID 37147454›Full record

ArticleJournal of community genetics2023

Knowledge, attitude, and perceptions about cancer genetic testing in clinical practice in Karachi, Pakistan.

Shameel Shafqat, Masooma Naseem, Masooma Rana, Zehra Naseem, Warda Ahmed, Muhammad Daniyal Musharraf, Arisha Zaheer, Ahmed Safiullah Shaikh, Muhammad Bazil Musharraf, Mahnoor Niaz and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of community genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Shameel ShafqatMedical College, The Aga Khan University, Karachi, Pakistan.
Masooma NaseemMedical College, Ziauddin University, Karachi, Pakistan.
Masooma RanaMedical College, The Aga Khan University, Karachi, Pakistan.
Zehra NaseemMedical College, The Aga Khan University, Karachi, Pakistan.
Warda AhmedMedical College, The Aga Khan University, Karachi, Pakistan.
Muhammad Daniyal MusharrafMedical College, The Aga Khan University, Karachi, Pakistan.
Arisha ZaheerLiaquat National Hospital and Medical College, Karachi, Pakistan.
Ahmed Safiullah ShaikhLiaquat National Hospital and Medical College, Karachi, Pakistan.
Muhammad Bazil MusharrafMedical College, The Aga Khan University, Karachi, Pakistan.
Mahnoor NiazMedical College, The Aga Khan University, Karachi, Pakistan.
Saifullah KhanMedical College, The Aga Khan University, Karachi, Pakistan.
Rabiya IrfanLiaquat National Hospital and Medical College, Karachi, Pakistan.
Areeba ImranLiaquat National Hospital and Medical College, Karachi, Pakistan.
Zahid MehmoodJinnah Postgraduate Medical Centre, Karachi, Pakistan. drzmpk@yahoo.com.
Aga Khan University · PKLiaquat National Hospital · PKJinnah Postgraduate Medical Center · PKZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare professionals (HCP) play an important role in the practical application of genetic screening tests but often feel inadequately prepared for cancer genetic testing (CGT) in clinical care. As the complexity of gene-related malignancies increases, it demands HCPs' preparedness to cater to patients' needs. Therefore, the aim of our study is to assess the knowledge, attitude, and practices of HCPs in Pakistan regarding the application of cancer genetics. Our cross-sectional survey was conducted from April 2022 to June 2022 amongst HCPs at a private and a governmental institution in Karachi, Pakistan. Non-probability random convenience sampling was used to select the population; however. non-clinical HCPs, as well as Interns, were excluded from our study. A total of 210 HCPs, 56.7% (119) bearing an experience of over 5 years of clinical experience, were included in this study. Most respondents from both hospitals deemed their knowledge inadequate, with only 2% (2) and 1.8% (2) being extremely knowledgeable, respectively. 68.6% (144) HCPs displayed a positive attitude towards CGT, with 55.2% (116) participants perceiving CGT in a positive light. As compared to the private sector, significantly more HCPs in the public sector dedicated ≥ 5 h/week for CME (P = 0.006), and were better prepared to counsel patients (P = 0.021) and interpret results concerning CGT (P = 0.020). Additionally, screening tests for specific cancer types were popularly considered a worthwhile avenue of investment to improve the current state of CGT in our healthcare system [47.6% (N = 100)]. Demonstrating a lack of knowledge among Pakistani doctors, our results call upon the need for additional training concerning CGT in both the public and private sectors alike. Understanding specific gaps in knowledge may further help enhance post-graduate training programs and eventually lead to effective incorporation of CGT into our healthcare setting.

Indexed as

AttitudesGenetic counselingGenetic literacyGenetic testingHealth literacyKnowledge

Identifiers

PMID37147454
PMCPMC10271944
OpenAlexW4372218514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.