Evidence map›Paper›PMID 37147440›Full record

ArticleScientific reports2023

Use of machine learning to assess the prognostic utility of radiomic features for in-hospital COVID-19 mortality.

Yuming Sun, Stephen Salerno, Xinwei He, Ziyang Pan, Eileen Yang, Chinakorn Sujimongkol, Jiyeon Song, Xinan Wang, Peisong Han, Jian Kang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yuming Sun *Department of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Stephen Salerno *Department of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Xinwei HeDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Ziyang PanDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Eileen YangDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Chinakorn SujimongkolDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Jiyeon SongDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Xinan WangDepartment of Environmental Health and Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA.
Peisong HanDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Jian KangDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
Michael W SjodingDivision of Pulmonary and Critical Care, Department of Internal Medicine, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, USA.
Shruti JollyDepartment of Radiation Oncology, University of Michigan Rogel Cancer Center, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, USA.
David C ChristianiDepartment of Environmental Health and Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA.
Yi LiDepartment of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA. yili@umich.edu.
University of Michigan–Ann Arbor · USBoston University · USHarvard University · US

Funding

Optimizing Clinician and AI Collaborations to Support Timely Management of Acute DyspneaR01HL158626 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael William Sjoding, Jenna Wiens · 2021 to 2026
$3.8M
New Statistical Methods for Modelling Cancer OutcomesR01CA249096 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yi Li · 2021 to 2026
$2.5M
Detecting racial disparities in cancer survival by integrating multiple high-dimensional observational studiesR01CA269398 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GUHA, SUBHARUP, LI, YI · 2022 to 2025
$1.3M
NCI NIH HHS R01 CA249096NCI NIH HHS R01 CA269398NHLBI NIH HHS R01 HL158626
6 · The paper itself

Abstract

As portable chest X-rays are an efficient means of triaging emergent cases, their use has raised the question as to whether imaging carries additional prognostic utility for survival among patients with COVID-19. This study assessed the importance of known risk factors on in-hospital mortality and investigated the predictive utility of radiomic texture features using various machine learning approaches. We detected incremental improvements in survival prognostication utilizing texture features derived from emergent chest X-rays, particularly among older patients or those with a higher comorbidity burden. Important features included age, oxygen saturation, blood pressure, and certain comorbid conditions, as well as image features related to the intensity and variability of pixel distribution. Thus, widely available chest X-rays, in conjunction with clinical information, may be predictive of survival outcomes of patients with COVID-19, especially older, sicker patients, and can aid in disease management by providing additional information.

Indexed as

COVID-19Hospital MortalityHospitalsHumansMachine LearningPrognosisRetrospective Studies

Identifiers

PMID37147440
PMCPMC10161188
OpenAlexW4372334648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.