ArticleScientific reports2023
Associations between cardiorespiratory fitness and cardiometabolic risk factors in children and adolescents with obesity.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of high-intensity interval training on cardiorespiratory fitness in adolescents with overweight or obesity: a systematic review and dose-response meta-analysis.Frontiers in physiology · 2026Pooled it
- Perinatal factors and their association with cardiometabolic profile in schoolchildren.Italian journal of pediatrics · 2026Article
- Associations of cardiorespiratory fitness and muscle strength during pregnancy with metabolic health outcomes and inflammatory parameters at 1-year postpartum in women after gestational diabetes.Cardiovascular diabetology. Endocrinology reports · 2025Article
- Supervised Machine Learning Algorithms for Fitness-Based Cardiometabolic Risk Classification in Adolescents.Sports (Basel, Switzerland) · 2025Article
- The associations of diet quality and cardiometabolic indicators in children and the mediation role of cardiorespiratory fitness.Frontiers in nutrition · 2025Article
- Investigation of Underlying Association between Anthropometric and Cardiorespiratory Fitness Markers among Overweight and Obese Adolescents in Canada.International journal of environmental research and public health · 2024Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
It is unclear if associations between cardiorespiratory fitness (CRF) and cardiometabolic risk factors are independent of degree of obesity, in children with obesity. The aim of this cross-sectional study on 151 children (36.4% girls), 9-17 years, from a Swedish obesity clinic, was to investigate associations between CRF and cardiometabolic risk factors, adjusted for body mass index standard deviation score (BMI SDS), in children with obesity. CRF was objectively assessed with the Åstrand-Rhyming submaximal cycle ergometer test, and blood samples (n = 96) and blood pressure (BP) (n = 84) according to clinical routine. Obesity specific reference values for CRF were used to create CRF levels. CRF was inversely associated with high-sensitivity C-reactive protein (hs-CRP), independent of BMI SDS, age, sex, and height. The inverse associations between CRF and diastolic BP did not remain significant when adjusted for BMI SDS. CRF and high-density lipoprotein cholesterol became inversely associated when adjusted for BMI SDS. Independent of degree of obesity, lower CRF is associated with higher levels of hs-CRP, as a biomarker of inflammation, in children with obesity and regular assessment of CRF should be encouraged. Future research in children with obesity should investigate if low-grade inflammation decreases when CRF is improved.
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