Evidence map›Paper›PMID 37146874›Full record

ArticleContemporary clinical trials2023

A randomized trial of acceptance-based behavioral therapy to improve mental health outcomes for LGBTQ+ persons: Study protocol.

Ethan Moitra, Leslie A Brick, Mary Kathryn Cancilliere, A Rani Elwy, A Maximillian Erbe, Natalie Fenn, Amy S Nunn, Peter Salhaney, Philip A Chan

Registry-linked trialOpen access · hybridAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05540067 (Improving Mental Health Among the LGBTQ+ Community Impacted by the COVID-19 Pandemic), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05540067 phase2active not recruitingnot on this map

Improving Mental Health Among the LGBTQ+ Community Impacted by the COVID-19 Pandemic

TypeinterventionalSponsorBrown UniversityRan2023 to 2026Enrolled240ConditionsAnxiety, DepressionArmsAcceptance-Based Behavior Therapy (ABBT), Treatment-as-Usual (TAU)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ethan MoitraDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA. Electronic address: ethan_moitra@brown.edu.
Leslie A BrickDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Mary Kathryn CancilliereDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA; Department of Psychiatry, Rhode Island Hospital, Providence, RI, USA.
A Rani ElwyDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA; Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
A Maximillian ErbeOpen Door Health, Rhode Island Public Health Institute, Providence, RI, USA.
Natalie FennDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA; Department of Psychiatry, Rhode Island Hospital, Providence, RI, USA.
Amy S NunnDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA; Department of Medicine, Alpert Medical School of Brown University, Providence, RI, USA; Open Door Health, Rhode Island Public Health Institute, Providence, RI, USA.
Peter SalhaneyOpen Door Health, Rhode Island Public Health Institute, Providence, RI, USA.
Philip A ChanDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA; Department of Medicine, Alpert Medical School of Brown University, Providence, RI, USA; Open Door Health, Rhode Island Public Health Institute, Providence, RI, USA.
Brown University · USProvidence College · USPublic Health Institute · USRhode Island Department of Health · US

Funding

Training in Child/Adolescent Biobehavioral HIV ResearchT32MH078788 · NIMH · RHODE ISLAND HOSPITAL · PI LARRY K BROWN · 2007 to 2026
$6.2M
Improving mental health among the LGBTQ+ community impacted by the COVID-19 pandemicRF1MH132348 · NIMH · BROWN UNIVERSITY · PI CHAN, PHILIP ANDREW, MOITRA, ETHAN · 2022 to 2022
$2.4M
NIMH NIH HHS RF1 MH132348NIMH NIH HHS T32 MH078788
6 · The paper itself

Abstract

backgroundDuring the COVID-19 pandemic, public health measures limited social interactions as an effective and protective intervention for all. For many, however, this social isolation exacerbated mental health symptoms. People who identify as lesbian, gay, bisexual, transgender, and queer (LGBTQ+) were already at elevated risk of anxiety and depression, relative to cisgender and heterosexual populations, and pandemic-related social isolation likely heightened these disparities. In our prior work with sexual and gender minorities, we developed and established feasibility and acceptability of a novel acceptance-based behavioral therapy (ABBT) intervention for HIV treatment. ABBT showed promise in improving social support and reducing mental health symptoms. In the current study, we investigate the efficacy of ABBT, compared to a treatment-as-usual control condition, in a full-scale randomized controlled trial to improve social support for LGBTQ+ persons living with anxiety and depression.

methodsTwo hundred forty LGBTQ+ adults with anxiety and/or depressive symptoms will be recruited and equally randomized to receive: (a) the ABBT intervention, consisting of two 30-40 min sessions plus treatment-as-usual (TAU), or (b) TAU only. Primary outcomes are interviewer-assessed anxiety and depressive symptoms. Secondary outcomes are self-reported anxiety and depressive symptoms. Experiential avoidance and social support are hypothesized mediators and presence of an anxiety and/or depressive disorder is a hypothesized moderator.

conclusionsABBT represents a novel, identify-affirming real-world approach to promoting social support as a means of improving mental health among individuals who identify as LGBTQ+. This study will contribute actionable data establishing the impact, mediational mechanisms, and effect modifiers of ABBT. CLINICALTRIALS: govregistration: NCT05540067.

Indexed as

COVID-19Sexual and Gender MinoritiesAdultBehavior TherapyFemaleHumansMaleOutcome Assessment, Health CarePandemicsRandomized Controlled Trials as TopicAcceptanceAnxietyBehavioral interventionDepressionLGBTQ+

Identifiers

PMID37146874
PMCPMC10155421
OpenAlexW4367839959

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.