Evidence map›Paper›PMID 37146514›Full record

SynthesisSeizure2023

Health consequences and daily life modifications in children and adolescents with epilepsy during the COVID-19 pandemic - a systematic review: Running Title: Covid-19 Pandemic in Children/Adolescents with Epilepsy.

Janise Dal-Pai, Michele Paula Dos Santos, Natalie da Silveira Donida, Matheus Ribeiro Cesarino, Victor Hugo Midões Santana de Oliveira, Magda Lahorgue Nunes

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Seizure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Janise Dal-PaiBrain Institute of Rio Grande do Sul - Pontifical Catholic University of Rio Grande do Sul (InsCer / PUCRS), Porto Alegre, Brazil.
Michele Paula Dos SantosExtension and Management of Continuing Education Activities Program - Pontifical Catholic University of Rio Grande do Sul (PEGA / PUCRS), Porto Alegre, Brazil.
Natalie da Silveira DonidaExtension and Management of Continuing Education Activities Program - Pontifical Catholic University of Rio Grande do Sul (PEGA / PUCRS), Porto Alegre, Brazil.
Matheus Ribeiro CesarinoExtension and Management of Continuing Education Activities Program - Pontifical Catholic University of Rio Grande do Sul (PEGA / PUCRS), Porto Alegre, Brazil.
Victor Hugo Midões Santana de OliveiraExtension and Management of Continuing Education Activities Program - Pontifical Catholic University of Rio Grande do Sul (PEGA / PUCRS), Porto Alegre, Brazil. Electronic address: victor.midoes@edu.pucrs.br.
Magda Lahorgue NunesProfessor of Neurology, School of Medicine - Pontifical Catholic University of Rio Grande do Sul (InsCer / PUCRS), Porto Alegre, Brazil. Electronic address: mlnunes@pucrs.br.
Pontifícia Universidade Católica do Rio Grande do Sul · BRInstituto do Cérebro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the impact of the COVID-19 pandemic on the health care and daily life of children and adolescents with epilepsy.

methodsThis systematic review followed the preferred reporting items guidelines and was registered on the PROSPERO platform (CRD42021255931). The PECO (Patient, Exposure, Comparison, Outcome) framework criteria were as follows: people with epilepsy (0-18 years old); exposed to the COVID-19 pandemic; and outcomes, including epilepsy type, time of clinical diagnosis, seizure exacerbation, treatment and medications, need for emergency because of seizures, sleep, behavior, comorbidities and/or concerns, social and/or economic impact, insurance status, electronic device use, telemedicine, and distance learning. Literature searches for cross-sectional and longitudinal studies were conducted on Embase and PubMed. The methodological quality of identified studies was assessed using the Newcastle‒Ottawa Scale (NOS).

resultsData were extracted from 23 eligible out of 597 identified articles and included 31,673 patients. The mean NOS scores for cross-sectional study design was 3.84/10, and for longitudinal, it was 3.5/8 stars. Seizure exacerbations were reported in three studies, difficulties with access to anti-seizure medications in two, changes in dosage in five, and visit postponed or cancelation in five studies. Problems with sleep were highlighted in three, issues related to distance learning in two, an increased time spent on electronic devices in three, and increased behavioral problems in eight studies. Telemedicine, when available, was described as useful and supporting patient's needs.

conclusionThe pandemic affected the health care and lifestyle of young individuals with epilepsy. The main problems described revolved around seizure control, accessing anti-seizure medication, sleep and behavioral complains.

Indexed as

COVID-19EpilepsyRunningAdolescentChildChild, PreschoolCross-Sectional StudiesHumansInfantInfant, NewbornPandemics

Identifiers

PMID37146514
PMCPMC10140054
OpenAlexW4367300055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.