Evidence map›Paper›PMID 37146281›Full record

ArticleDiabetes2023

"FunDNAmethyl" Mechanism for Developmental Restriction of a β-Cell Subpopulation.

Cristina Aguayo-Mazzucato, Michael L Stitzel

Abstract readEditorialComment
In one paragraph

Article in Diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Cristina Aguayo-MazzucatoSection on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA.ORCID 0000-0001-5402-1382
Michael L StitzelThe Jackson Laboratory for Genomic Medicine, Farmington, CT.ORCID 0000-0001-5630-559X

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI JEAN E. SCHAFFER · 1986 to 2026
$50.5M
Genetic programming of human islet metabolic and endoplasmic reticulum (ER) stress responses in diabetesR01DK118011 · NIDDK · JACKSON LABORATORY · PI Michael Lee Stitzel · 2021 to 2026
$4.9M
Adaptive epigenetic mechanisms of beta and immune cells in autoimmune diabetesR01DK129523 · NIDDK · YALE UNIVERSITY · PI HEROLD, KEVAN C · 2021 to 2024
$2.7M
Regulation and Function of the Type 2 Diabetes-Associated C2CD4A/B LocusR01DK117137 · NIDDK · JACKSON LABORATORY · PI STITZEL, MICHAEL LEE · 2019 to 2023
$2.1M
Elucidating and targeting beta-cell senescence and its SASPR01DK132535 · NIDDK · JOSLIN DIABETES CENTER · PI Cristina Aguayo-Mazzucato · 2022 to 2026
$2.1M
NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R01 DK117137NIDDK NIH HHS R01 DK118011NIDDK NIH HHS R01 DK129523NIDDK NIH HHS R01 DK132535
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA MethylationTyrosine 3-MonooxygenaseProtein Processing, Post-TranslationalTyrosine 3-Monooxygenase

Identifiers

PMID37146281
PMCPMC10130483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.