Evidence map›Paper›PMID 37145957›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2023

Sex hormones impact early maturation and immune response in the arteriovenous fistula mouse model.

Keyuree Satam, Yuichi Ohashi, Carly Thaxton, Luis Gonzalez, Ocean Setia, Hualong Bai, Yukihiko Aoyagi, Yangzhouyun Xie, Weichang Zhang, Bogdan Yatsula and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Sex as a biological variable for cardiovascular physiology.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  8. Article
  9. The rodent models of arteriovenous fistula.Frontiers in cardiovascular medicine · 2024
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Keyuree SatamYale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0002-7398-5301
Yuichi OhashiVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.
Carly ThaxtonYale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0001-9270-8708
Luis GonzalezYale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0003-2877-7287
Ocean SetiaVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.
Hualong BaiVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0003-4039-414X
Yukihiko AoyagiVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0003-4165-0264
Yangzhouyun XieDivision of Vascular Surgery and Endovascular Therapy, Department of Surgery, Yale School of Medicine, New Haven, Connecticut, United States.
Weichang ZhangVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.
Bogdan YatsulaVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0002-7723-1048
Kathleen A MartinSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0002-1748-0034
Yujun CaiDivision of Vascular Surgery and Endovascular Therapy, Department of Surgery, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0002-0323-6700
Alan DardikVascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0001-5022-7367
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Manipulating the matrix to improve arteriovenous fistula patencyR01HL144476 · NHLBI · YALE UNIVERSITY · PI Alan Dardik · 2019 to 2026
$5.6M
Adaptive immunity regulates arteriovenous fistula remodelingR01HL162580 · NHLBI · YALE UNIVERSITY · PI Alan Dardik · 2023 to 2026
$3.0M
Short Term Research Training: Students in Health Professional SchoolsT35DK104689 · NIDDK · YALE UNIVERSITY · PI LLOYD G CANTLEY, Sarwat I Chaudhry · 2015 to 2026
$2.6M
CRR LIGAND ASSAY AND ANALYSIS CORER24HD102061 · NICHD · UNIVERSITY OF VIRGINIA · PI HAISENLEDER, DANIEL J. · 2019 to 2023
$2.2M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL144476NHLBI NIH HHS R01 HL162580NICHD NIH HHS R24 HD102061NIDDK NIH HHS T35 DK104689
6 · The paper itself

Abstract

Arteriovenous fistulae (AVF) fail to mature more frequently in female patients compared with male patients, leading to inferior outcomes and decreased utilization. Since our mouse AVF model recapitulates sex differences in human AVF maturation, we hypothesized that sex hormones mediate these differences during AVF maturation. C57BL/6 mice (9-11 wk) were treated with aortocaval AVF surgery and/or gonadectomy. AVF hemodynamics were measured via ultrasound (

Indexed as

Arteriovenous FistulaArteriovenous Shunt, SurgicalAnimalsCD8-Positive T-LymphocytesDisease Models, AnimalFemaleHumansImmunityMaleMiceMice, Inbred C57BLRenal DialysisSexual MaturationTestosteroneTestosteronearteriovenous fistulahemodynamicsimmunitysex differences

Identifiers

PMID37145957
PMCPMC10243550
OpenAlexW4372271820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.