Evidence map›Paper›PMID 37145269›Full record

ArticleJournal of nephrology2023

Atypical HUS with multiple complement system mutations triggered by synthetic psychoactive drug abuse: a case report.

Ivo Jelicic, Vedran Kovacic, Mirko Luketin, Marijana Mikacic, Dijana Boric Skaro

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Atypical hemolytic uremic syndrome with aFrontiers in pediatrics · 2025
    Article
  2. Article
  3. Review
  4. The Rationale of Complement Blockade of the MCPInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ivo JelicicInternal Medicine Department, Nephrology and Haemodialysis Division, School of Medicine, University Hospital of Split, University of Split, 21000, Split, Croatia.
Vedran KovacicInternal Medicine Department, Division of Emergency and Intensive Medicine with Clinical Pharmacology and Toxicology, School of Medicine, University Hospital of Split, University of Split, Spinciceva 1, 21000, Split, Croatia. vedran.kovacic.split@gmail.com.ORCID http://orcid.org/0000-0002-9854-2611
Mirko LuketinInternal Medicine Department, Nephrology and Haemodialysis Division, School of Medicine, University Hospital of Split, University of Split, 21000, Split, Croatia.
Marijana MikacicInternal Medicine Department, Division of Emergency and Intensive Medicine with Clinical Pharmacology and Toxicology, School of Medicine, University Hospital of Split, University of Split, Spinciceva 1, 21000, Split, Croatia.
Dijana Boric SkaroInternal Medicine Department, Nephrology and Haemodialysis Division, School of Medicine, University Hospital of Split, University of Split, 21000, Split, Croatia.
University of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical hemolytic uremic syndrome is a rare disorder with an estimated annual incidence of about two cases per million in the adult population. It is caused by the overactivation of the alternative pathway of the complement system. The disease can be triggered by many factors, including pregnancy, viral diseases, and sepsis; approximately 30% of atypical hemolytic uremic syndrome cases are caused by unknown processes. We present a case of a patient with C3-complement system mutations and aHUS triggered by the use of a new synthetic psychoactive drug.

Indexed as

Atypical Hemolytic Uremic SyndromeAdultComplement C3HumansMutationPsychotropic DrugsRare DiseasesComplement C3Psychotropic DrugsaHUSAmphetamineEculizumabSynthetic drugs

Identifiers

PMID37145269
PMCPMC10161151
OpenAlexW4372293509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.