Trial reportClinical oral investigations2023
Secondary alveolar cleft grafting using autogenous mineralized plasmatic matrix (MPM) versus cancellous bone particles derived from anterior iliac crest.
Trial report in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Alveolar cleft reconstruction using autogenous double iliac corticocancellous bone blocks technique versus particulate autogenous spongy bone graft from anterior iliac crest.Clinical oral investigations · 2025Trial
- Hexahedral Graft Bed Formation Enhances Outcomes in Secondary Alveolar Bone Grafting: Surgical Technique and Graft Volume Thresholds.Plastic and reconstructive surgery. Global open · 2026Article
- Sticky bone in regenerative dentistry: a paradigm shift in graft stability or a promising technique still under scrutiny?Annals of medicine and surgery (2012) · 2026Review
- Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft-A Review.Children (Basel, Switzerland) · 2025Review
- Integrating Virtual Surgical Planning and 3D-Printed Tools with Iliac Bone Grafts for Orbital and Zygomatic Reconstruction in Hemifacial Microsomia Patients.Journal of clinical medicine · 2023Article
- Three-dimensional printed titanium mesh combined with iliac cancellous bone in the reconstruction of mandibular defects secondary to ameloblastoma resection.BMC oral health · 2023Article
- Graft materials and regenerative strategies in secondary alveolar bone grafting: A scoping review of randomized clinical trials.Journal of oral biology and craniofacial researchReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe essential concern of alveolar cleft grafting in patients of cleft lip and palate at the mixed dentition phase is to gain bone within the cleft area that provides closure of the oronasal communication with continuous and stable maxilla for future cleft teeth eruption or implantation. This study aimed to compare the effectiveness of mineralized plasmatic matrix (MPM) versus cancellous bone particles harvested from anterior iliac crest in secondary alveolar cleft grafting. PATIENTS AND
methodsThis prospective randomized controlled trial was conducted on ten patients with unilateral complete alveolar cleft requiring cleft reconstruction. Patients were randomly divided into two equal groups; group (1) included 5 patients who received particulate cancellous bone derived from anterior iliac crest (control group) and group (2) included 5 patients who received MPM graft prepared from cancellous bone derived from anterior iliac crest (study group). All patients received CBCT preoperatively, immediately postoperatively and after 6 months. On the CBCT, graft's volume, labio-palatal width, and height were measured and compared.
resultsThe outcome of the studied patients 6 months postoperatively showed that the control group had significant decrease in the graft volume, labio-palatal width, and height compared to the study group.
conclusionMPM allowed for the integration of bone graft particles inside a fibrin network, which offers positional stability of the bone particles, thus preserving their shape with subsequent "in situ" immobilization of the graft components. This conclusion was reflected positively in terms of maintained graft volume, width, and height compared to that of the control group. CLINICAL RELEVANCE: MPM allowed for maintenance of grafted ridge volume, width, and height.
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