Evidence map›Paper›PMID 37145113›Full record

ArticleeLife2023

Two enhancer binding proteins activate σ

Ericka D Surrett, Kirsten R Guckes, Shyan Cousins, Terry B Ruskoski, Andrew G Cecere, Denise A Ludvik, C Denise Okafor, Mark J Mandel, Tim I Miyashiro

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. A single point mutation is sufficient to driveJournal of bacteriology · 2025
    Article
  2. Article
  3. Article
  4. Journal of bacteriology · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ericka D SurrettDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.
Kirsten R GuckesDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.ORCID 0000-0002-0929-3351
Shyan CousinsDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.
Terry B RuskoskiDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.
Andrew G CecereDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.
Denise A LudvikDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0001-7280-7362
C Denise OkaforDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.ORCID 0000-0001-7374-1561
Mark J MandelDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0001-6506-6711
Tim I MiyashiroDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, United States.ORCID 0000-0002-5016-1641
Pennsylvania State University · USUniversity of Wisconsin–Madison · US

Funding

Heterogeneity in bacterial quorum sensing during infectionR01GM129133 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MIYASHIRO, TIMOTHY · 2018 to 2023
$2.0M
Genetic analysis of beneficial bacterial colonizationR35GM148385 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Mark J Mandel · 2023 to 2026
$1.8M
Impact of quorum sensing on type VI secretion activities during symbiosis establishmentF32AI147543 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI GUCKES, KIRSTEN R · 2020 to 2022
$212k
NIAID NIH HHS F32 AI147543NIGMS NIH HHS R01 GM129133NIGMS NIH HHS R35 GM148385
6 · The paper itself

Abstract

To colonize a host, bacteria depend on an ensemble of signaling systems to convert information about the various environments encountered within the host into specific cellular activities. How these signaling systems coordinate transitions between cellular states in vivo remains poorly understood. To address this knowledge gap, we investigated how the bacterial symbiont

Indexed as

DNA-Binding ProteinsSymbiosisAliivibrio fischeriAnimalsBacterial ProteinsDecapodiformesQuorum SensingTranscription FactorsBacterial ProteinsDNA-Binding ProteinsTranscription FactorsEuprymna scolopesgene regulationinfectious diseasemicrobiologysigma factorsymbiosisVibrio fischeriVibrionaceae

Identifiers

PMID37145113
PMCPMC10162802
OpenAlexW4372334594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.