ArticleGeneral psychiatry2023
Correlation between serum lipid profiles and cognitive impairment in old age: a cross-sectional study.
Article in General psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 15 citations in OpenAlex.
- The effect of milk fat globule membrane phospholipid supplementation on cognitive function in older adults with subjective memory complaints-a randomized, double-blind, placebo-controlled trial.The American journal of clinical nutrition · 2025Trial
- Elevated endogenous glucagon-like peptide-1 as a novel Alzheimer's disease biomarker associated with neuroinflammation and Aβ pathology.General psychiatry · 2026Article
- Effects of Sleeve Gastrectomy on Cognitive Function, Metabolic Indexes and Related Hormones in Adolescents with Obesity.Obesity surgery · 2026Article
- Ameliorative effects of omega-3 against profenofos-induced neurotoxicity in rats via PI3K/AKT pathway.Scientific reports · 2026Article
- Dementia risk prediction in individuals with prediabetes or diabetes: A novel multi-protein score with biological pathway analysis.General psychiatry · 2026Article
- Development and Validation of a Risk-Prediction Nomogram for Nutritional Risk in Non-Dialysis Chronic Renal Failure Patients.Risk management and healthcare policy · 2026Article
- Vascular risk factor variability and cognitive impairment in older adults a community-based retrospective study.Scientific reports · 2025Article
- Low serum triglycerides related to delayed neurocognitive recovery in geriatric oral and maxillofacial surgery patients: A prospective cohort study.Lipids in health and disease · 2025Article
- A cross sectional study of the diabetes mediated GGT to HDL ratio and cognitive function in older adults.Scientific reports · 2025Article
- Prevalence, incidence and modifiable factors for subtypes of mild cognitive impairment: results from the Longitudinal Ageing Study in China.General psychiatry · 2025Article
- Association of low-density lipoprotein/high-density lipoprotein ratio with cognition, Alzheimer's disease biomarkers and brain structure.Frontiers in aging neuroscience · 2025Article
- Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments.Open medicine (Warsaw, Poland) · 2025Review
- Exploring the relationship between lipid metabolism and cognition in individuals living with stable-phase Schizophrenia: a small cross-sectional study using Olink proteomics analysis.BMC psychiatry · 2024Article
- Prevalence and patterns of vitamin D deficiency and its role in cognitive functioning in a cohort from South India.Scientific reports · 2024Article
- Relationship between Plasma Lipid Profile and Cognitive Status in Early Alzheimer Disease.International journal of molecular sciences · 2024Article
- Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates.Frontiers in neurology · 2024Article
- Prevalence of dementia and the attributable contributions of modifiable risk factors in China.General psychiatry · 2023Article
- Blood lipids as accessible biomarkers for early dementia risk screening: Bridging diagnostic gaps in resource-limited settings.Journal of Alzheimer's disease reportsReview
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The correlation between cognitive function and lipid profiles, including total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides, is inconsistent. Aims: This cross-sectional study investigated the association between serum lipid levels and the prevalence of cognitive impairment among community-dwelling older adults and explored this difference in association by gender and urban-rural residency. Methods: Participants aged 65 and above in urban and rural areas were recruited between 2018 and 2020, selected from the Hubei Memory and Aging Cohort Study. Detailed neuropsychological evaluations, clinical examinations and laboratory tests were conducted in community health service centres. Multivariate logistic regression was used to analyse the correlation between serum lipid profiles and the prevalence of cognitive impairment. Results: We identified 1 336 cognitively impaired adults (≥65 years)-1 066 with mild cognitive impairment and 270 with dementia-from 4 746 participants. Triglycerides level was correlated with cognitive impairment in the total sample (χ Conclusions: There are gender and urban-rural differences in the correlation of serum lipids with cognitive impairment. High triglycerides levels may be a protective factor for cognitive function in older urban men, while high LDL-C levels may be a risk factor for cognitive function in older rural women.
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