Evidence map›Paper›PMID 37144090›Full record

ReviewFrontiers in neuroscience2023

The endocannabinoid system and breathing.

Beth M Wiese, Angelica Alvarez Reyes, Todd W Vanderah, Tally M Largent-Milnes

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Recommendations for the Clinical Management and Prevention of Pediatric Cannabis Edible Ingestions.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  3. CBPharmacological research · 2025
    Article
  4. Role of the Endocannabinoid System in Fibromyalgia.Current issues in molecular biology · 2025
    Review
  5. Article
  6. Review
  7. ΔCardiovascular toxicology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Beth M WieseDepartment of Pharmacology, University of Arizona, Tucson, AZ, United States.
Angelica Alvarez ReyesDepartment of Pharmacology, University of Arizona, Tucson, AZ, United States.
Todd W VanderahDepartment of Pharmacology, University of Arizona, Tucson, AZ, United States.
Tally M Largent-MilnesDepartment of Pharmacology, University of Arizona, Tucson, AZ, United States.
University of Arizona · US

Funding

Endocannabinoid Targeting for Opioid Induced Respiratory DepressionR01DA056608 · NIDA · UNIVERSITY OF ARIZONA · PI Tally Marie Milnes, TODD W VANDERAH · 2022 to 2026
$2.7M
Primary Afferent Transmission in the Trigeminal Dorsal HornF32DE022499 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MILNES, TALLY MARIE · 2011 to 2014
$127k
NIDA NIH HHS R01 DA056608NIDCR NIH HHS F32 DE022499
6 · The paper itself

Abstract

Recent changes in cannabis accessibility have provided adjunct therapies for patients across numerous disease states and highlights the urgency in understanding how cannabinoids and the endocannabinoid (EC) system interact with other physiological structures. The EC system plays a critical and modulatory role in respiratory homeostasis and pulmonary functionality. Respiratory control begins in the brainstem without peripheral input, and coordinates the preBötzinger complex, a component of the ventral respiratory group that interacts with the dorsal respiratory group to synchronize burstlet activity and drive inspiration. An additional rhythm generator: the retrotrapezoid nucleus/parafacial respiratory group drives active expiration during conditions of exercise or high CO

Indexed as

cannabinoid receptorscannabinoidsendocannabinoid systemopioidsrespiratory system

Identifiers

PMID37144090
PMCPMC10153446
OpenAlexW4366266954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.