ArticleAnnals of gastroenterology
Rapid on-site evaluation (ROSE) versus macroscopic on-site evaluation (MOSE) for endoscopic ultrasound-guided sampling of solid pancreatic lesions: a paired comparative analysis using newer-generation fine needle biopsy needles.
Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 23 citations in OpenAlex.
- Multimodal imaging platform for rapid non-destructive evaluation of pancreatic puncture specimens.Journal of biomedical optics · 2026Article
- Determinants of single‑pass specimen adequacy in endobronchial ultrasound-guided transbronchial needle aspiration: a real-world study.Journal of thoracic disease · 2026Article
- Slide-free, point-of-care imaging of core needle biopsies for rapid histologic assessment.Biomedical optics express · 2026Article
- Diagnostic accuracy and safety of endoscopic ultrasound-guided fine needle biopsy for evaluating mediastinal pathologies.World journal of gastrointestinal endoscopy · 2026Article
- Optimal Puncture Number and Tissue Evaluation Method in Endoscopic Ultrasound-Guided Fine-Needle Biopsy for Patients with Malignant Neoplasm of Pancreas.Diagnostics (Basel, Switzerland) · 2026Article
- Ensuring Quality in Interventional Cytopathology.Acta cytologica · 2026Review
- Cost of lung cancer diagnosis: cost differences between national health system and private sector.Lung cancer management · 2025Review
- Role of endoscopic ultrasound in diagnosis and management of autoimmune pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Review
- Comparison of standardWorld journal of methodology · 2025Article
- EUS FNAC without rapid on-site evaluation is comparable to EUS FNB with macroscopic on-site evaluation in evaluation of intra-abdominal masses.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Observational
- The Endoscopic Ultrasonography and Fine Needle Aspiration Agreement in Patients with Pancreatic Cystic Lesions, in Tehran, Iran.Middle East journal of digestive diseases · 2025Article
- Solid pancreatic lesions: etiology, morphology and utility of macroscopic on-site evaluation in predicting good yield of endoscopic ultrasound-guided biopsy.Przeglad gastroenterologiczny · 2025Article
- The role of rapid on-site evaluation in pancreatic lesion: a systematic review and meta-analysis of randomized control trials.Therapeutic advances in gastroenterology · 2025Article
- Endoscopic Ultrasound-Guided Pancreatic Tissue Sampling: Lesion Assessment, Needles, and Techniques.Medicina (Kaunas, Lithuania) · 2024Review
- Role of macroscopic on-site evaluation of endoscopic ultrasound-guided fine-needle aspiration/biopsy: Results of a multicentric prospective study.World journal of gastrointestinal endoscopy · 2024Article
- EUS-FNA versus EUS-FNB in Pancreatic Solid Lesions ≤ 15 mm.Diagnostics (Basel, Switzerland) · 2024Article
- [Challenges of cytopathological pancreas diagnostics].Pathologie (Heidelberg, Germany) · 2024Review
- Multicenter, randomized controlled trial of EUS-guided fine-needle biopsy using a fork-tip needle with macroscopic or rapid on-site evaluation for pancreatic lesions (HEndoscopic ultrasoundArticle
- Diagnostic performance of EUS-guided tissue acquisition for solid pancreatic lesions ≤10 mm.Endoscopic ultrasoundArticle
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Rapid on-site examination (ROSE) during endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) has been a subject of debate. We compared the yield of EUS-FNB with adequacy assessed using macroscopic on-site evaluation (MOSE), and smear cytology with adequacy confirmed by ROSE, acquired using the same needle. Methods: Consecutive patients with solid pancreatic lesions (SPLs) who underwent EUS-FNB of pancreatic solid lesions between January 2021 and July 2022 were included. Demographic details, site and size of lesion, number of passes, and the diagnosis by cytology and histopathology of core tissue were noted. The first pass was used for ROSE adequacy assessment and was subsequently sent for cytological assessment. Additional passes were taken subsequently to acquire core tissue. Adequacy was confirmed by MOSE (whitish core of more than 4 mm). Final cytology and histopathology (HPE) were compared for diagnostic accuracy. Results: One hundred fifty-five patients were included in the analysis during the study period (mean age 55.1+12.9 years; 60% male; 77% in pancreatic head; median size 3.7 cm). The final diagnosis was malignancy in 129, while 26 were negative for malignancy. Sensitivity and specificity for ROSE with cytology in detecting malignant SPLs were 96.9% and 100%, respectively. HPE with MOSE had sensitivity and specificity of 96.1% and 100%, respectively. A comparison of diagnostic accuracy showed no significant difference (P>0.99) between HPE with MOSE and ROSE with cytology, using an FNB needle. Conclusion: MOSE is as good as ROSE in terms of diagnostic yield for solid pancreatic lesions sampled using newer-generation EUS biopsy needles.
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