Evidence map›Paper›PMID 37144003›Full record

ArticleFrontiers in neurology2023

Therapeutic education for empowerment and engagement in patients with Parkinson's disease: A non-pharmacological, interventional, multicentric, randomized controlled trial.

Maria Francesca De Pandis, Margherita Torti, Rossella Rotondo, Lanfranco Iodice, Maria Levi Della Vida, Miriam Casali, Laura Vacca, Fabio Viselli, Valeria Servodidio, Stefania Proietti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Supporting Medication Adherence in Parkinson's Through Education: A Scoping Review of Interventions.Health expectations : an international journal of public participation in health care and health policy · 2026
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Maria Francesca De PandisSan Raffaele Cassino, Cassino, Italy.
Margherita TortiIRCCS San Raffaele Roma, Rome, Italy.
Rossella RotondoSan Raffaele Cassino, Cassino, Italy.
Lanfranco IodiceHealth Management, University Hospital "Federico II", Naples, Italy.
Maria Levi Della VidaSan Raffaele Cassino, Cassino, Italy.
Miriam CasaliIRCCS San Raffaele Roma, Rome, Italy.
Laura VaccaIRCCS San Raffaele Roma, Rome, Italy.
Fabio ViselliSan Giovanni Battista Hospital, Rome, Italy.
Valeria ServodidioSan Raffaele Cassino, Cassino, Italy.
Stefania ProiettiIRCCS San Raffaele Roma, Rome, Italy.
Fabrizio StocchiIRCCS San Raffaele Roma, Rome, Italy.
IRCCS Ospedale San Raffaele · ITUniversità degli studi di Cassino e del Lazio Meridionale · ITAzienda Ospedaliero Universitaria San Giovanni Battista · ITMinistero della Salute · ITSan Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In 1997 the European Parkinson's Disease Associations launched the Charter for People with Parkinson's disease that stated the right of patients to be informed and trained on the disease, its course, and treatments available. To date, few data analyzed the effectiveness of education program on motor and non-motor symptoms of PD. Objective: The aim of this study was to evaluate the efficacy of an education program as it was a pharmacological treatment, thus choosing as the primary endpoint the change in daily OFF hours, the most widely used outcome in pharmaceutical clinical trials on PD patients with motor fluctuations. Secondary outcomes were change in motor and non-motor symptoms, quality of life and social functioning. The long-term efficacy of the education therapy was also evaluated by analyzing data collected at 12- and 24-weeks follow-up outpatient visits. Methods: One hundred and twenty advanced patients and their caregivers were assigned to the intervention or control group in a single-blind, multicentric, prospective, randomized study evaluating an education program structured in individual and group sessions over a 6-weeks period.At the end of study, the intervention group showed a significant reduction in daily OFF hours compared to control patients (-1.07 ± 0.78 vs. 0.09 ± 0.35, Conclusion: The results obtained demonstrated that education programs may translate in a notable improvement in motor fluctuations and non-motor symptoms in advanced PD patients.

Indexed as

caregiversempowermentmotor fluctuationsParkinson’s diseasepatient education programrehabilitation

Identifiers

PMID37144003
PMCPMC10151770
OpenAlexW4366290461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.