ArticleFrontiers in public health2023
Severe Chagas disease in Ecuador: a countrywide geodemographic epidemiological analysis from 2011 to 2021.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- One health approach to chagas disease: a systematic review on the integration of human, animal, and environmental health.Frontiers in health services · 2026Pooled it
- Phlebotomine sand fly fauna characterization and Bartonella bacilliformis DNA detection in Pintomyia (Pifanomyia) robusta at the Ecuador-Peru frontier.PLoS neglected tropical diseases · 2026Article
- Left Atrial Thrombus and Cardioembolic Stroke in Chagas Cardiomyopathy Presenting with Atrial Flutter: A Case Report.Journal of clinical medicine · 2026Article
- Paradoxes of Elimination and Persistence: Neglected Tropical Diseases in Ecuador Compared to Latin America and the Caribbean.Journal of tropical medicine · 2026Review
- Clinical and epidemiological characterization of heart failure patients in a high-altitude setting: a retrospective study at a tertiary hospital in Quito, Ecuador.Frontiers in cardiovascular medicine · 2026Article
- Cardioembolic stroke in Chagas disease: unraveling the underexplored connection through a systematic review.Tropical diseases, travel medicine and vaccines · 2024Review
- Spatio-temporal distribution of hospitalizations for chronic Chagas disease and risk factors associated with in-hospital mortality and surgical intervention in Chile.PLoS neglected tropical diseases · 2024Article
- Chagas disease as an underrecognized cause of stroke: implications for public health.Frontiers in medicine · 2024Article
- Beyond the acute phase: a comprehensive literature review of long-term sequelae resulting from infectious diseases.Frontiers in cellular and infection microbiology · 2024Review
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Authors and funding
8 authors.
Funding
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Abstract
Background: Chagas disease is a neglected and often forgotten tropical disease caused by the Methodology: We analyzed the morbidity and mortality rates of severe Chagas disease in Ecuador on a nationwide, population-based level. Hospitalization cases and deaths were also examined based on altitude, including low (< 2,500 m) and high (> 2,500 m) altitudes, according to the International Society. Data was retrieved from the National Institute of Statistics and Census hospital admissions and in-hospital mortality databases from 2011 to 2021. Results: A total of 118 patients have been hospitalized in Ecuador since 2011 due to Chagas disease. The overall in-hospital mortality rate was 69.4% ( Conclusion: Chagas disease is a severe parasitic condition that primarily affects rural and poorer areas of Ecuador. Men are more likely to be infected due to differences in work and sociocultural activities. Using average elevation data, we conducted a geodemographic analysis to assess incidence rates by altitude. Our findings indicate that the disease is more common at low and moderate altitudes, but recent increases in cases at higher altitudes suggest that environmental changes, such as global warming, could be driving the proliferation of disease-carrying vectors in previously unaffected areas.
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