Evidence map›Paper›PMID 37143783›Full record

ArticleFrontiers in psychiatry2023

The relationship of trait-like compassion with epigenetic aging: The population-based prospective Young Finns Study.

Henrik Dobewall, Liisa Keltikangas-Järvinen, Saara Marttila, Pashupati P Mishra, Aino Saarinen, C Robert Cloninger, Igor Zwir, Mika Kähönen, Mikko Hurme, Olli Raitakari and 2 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Henrik DobewallFaculty of Education, VISE Research Unit, Faculty of Education and Psychology, University of Oulu, Oulu, Finland.
Liisa Keltikangas-JärvinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Saara MarttilaMolecular Epidemiology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Pashupati P MishraMolecular Epidemiology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Aino SaarinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
C Robert CloningerDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Igor ZwirDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mikko HurmeDepartment of Microbiology and Immunology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Olli RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Terho LehtimäkiMolecular Epidemiology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mirka HintsanenFaculty of Education, VISE Research Unit, Faculty of Education and Psychology, University of Oulu, Oulu, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Helping others within and beyond the family has been related to living a healthy and long life. Compassion is a prosocial personality trait characterized by concern for another person who is suffering and the motivation to help. The current study examines whether epigenetic aging is a potential biological mechanism that explains the link between prosociality and longevity. Methods: We used data from the Young Finns Study that follows six birth-cohorts from age 3-18 to 19-49. Trait-like compassion for others was measured with the Temperament and Character Inventory in the years 1997 and 2001. Epigenetic age acceleration and telomere length were measured with five DNA methylation (DNAm) indicators (DNAmAgeHorvath, IEAA_Hannum, EEAA_Hannum, DNAmPhenoAge, and DNAmTL) based on blood drawn in 2011. We controlled for sex, socioeconomic status in childhood and adulthood, and body-mass index. Results and discussion: An association between higher compassion in 1997 and a less accelerated DNAmPhenoAge, which builds on previous work on phenotypic aging, approached statistical significance in a sex-adjusted model (

Indexed as

compassionDNA methylationDNAmPhenoAgeepigenetic aginglongevityprosocial personalitytemperament and character inventory

Identifiers

PMID37143783
PMCPMC10151573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.