Evidence map›Paper›PMID 37143741›Full record

ArticleFrontiers in cellular and infection microbiology2023

Prevalence and molecular characteristics of polymyxin-resistant

Chenlu Xiao, Xuming Li, Lianjiang Huang, Huiluo Cao, Lizhong Han, Yuxing Ni, Han Xia, Zhitao Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Global prevalence of mutation in theFrontiers in microbiology · 2024
    Pooled it
  2. Article
  3. Article
  4. Characterization of anAntibiotics (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chenlu XiaoDepartment of Laboratory Medicine, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xuming LiDepartment of Scientific Affairs, Hugobiotech Co., Ltd., Beijing, China.
Lianjiang HuangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, China.
Huiluo CaoDepartment of Microbiology, The University of Hongkong, Hong Kong, Hong Kong SAR, China.
Lizhong HanDepartment of Laboratory Medicine, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuxing NiDepartment of Infection Control, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Han XiaDepartment of Scientific Affairs, Hugobiotech Co., Ltd., Beijing, China.
Zhitao YangDepartment of Emergency, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNThe Second Affiliated Hospital of Xiamen Medical College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Polymyxin-resistant Methods: Polymyxin-resistant Results: Of the 1,216 isolates collected, 32 (2.6%) across 12 wards were polymyxin-resistant (minimum inhibitory concentration (MIC) range, PMB 4-256 mg/ml, and colistin 4 ≥ 16 mg/ ml). A total of 28 (87.5%) of the polymyxin-resistant isolates had reduced susceptibility to imipenem and meropenem (MIC ≥ 16 mg/ml). Of the 32 patients, 15 patients received PMB treatment and 20 survived before discharge. The phylogenetic tree of these isolates showed they belonged to different clones and had multiple origins. The polymyxin-resistant Discussion: In our study, a low prevalence of polymyxin-resistant

Indexed as

Escherichia coli ProteinsPolymyxinsAnti-Bacterial AgentsDrug Resistance, BacterialEast Asian PeopleEscherichia coliHospitals, TeachingHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMultilocus Sequence TypingPhylogenyPrevalenceAnti-Bacterial AgentsEscherichia coli ProteinsMCR-1 protein, E coliPolymyxinscomparative genomicsEnterobacteralesphenotypespolymyxin-resistanceprevalence

Identifiers

PMID37143741
PMCPMC10151768
OpenAlexW4366292012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.