Evidence map›Paper›PMID 37143648›Full record

ArticleFrontiers in immunology2023

Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive

Benjamin R Cassidy, Sreemathi Logan, Julie A Farley, Daniel B Owen, William E Sonntag, Douglas A Drevets

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Benjamin R CassidyDepartment of Internal Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
Sreemathi LoganDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
Julie A FarleyDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
Daniel B OwenDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
William E SonntagDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
Douglas A DrevetsDepartment of Internal Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
University of Oklahoma Health Sciences Center · US

Funding

Visualizing insulin actions on neuronal metabolism and function using fluorescent biosensorsP20GM125528 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Marisol Castillo-Castrejon · 2019 to 2026
$17.8M
IGF-1 Regulation of Astrocyte Mitochondrial Metabolism and Redox Homeostasis in Brain AgingR00AG056662 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI LOGAN, SREEMATHI · 2020 to 2022
$996k
NIA NIH HHS R00 AG056662NIGMS NIH HHS P20 GM125528
6 · The paper itself

Abstract

Background: Neuro-cognitive impairment is a deleterious complication of bacterial infections that is difficult to treat or prevent. Methods: Male C57BL/6J mice (age 8 wks) were injected with neuroinvasive Results: Changes suggesting cognitive decline were observed 1 mo p.i. in both groups of infected mice compared with uninfected controls, but were more widespread and significantly worse 4 mo p.i. and most notably after Conclusions: Systemic infection by neuroinvasive as well as non-neuroinvasive

Indexed as

Cognitive DysfunctionListeria monocytogenesListeriosisAnimalsCD8-Positive T-LymphocytesMaleMiceMice, Inbred C57BLbacterial meningitisCD8+ tissue-resident memory T lymphocytescognitive dysfunctioncognitive testingListeria monocytogenesneuroinflammation

Identifiers

PMID37143648
PMCPMC10151798
OpenAlexW4366293946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.